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James R Halpert

Showing results (41-50 of 108) with videos related to

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Chemical Research in Toxicology|June 18, 2002
Site-directed mutagenesis of cytochrome P450eryF: implications for substrate oxidation, cooperativity, and topology of the active siteKishore K Khan, You Ai He, You Qun He, et al.
Protein Engineering, Design & Selection : PEDS|October 20, 2006
Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxideSantosh Kumar, Ling Sun, Hong Liu, et al.
Biochemistry|January 3, 2007
Mechanism of interactions of alpha-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probeTamara N Tsalkova, Nadezhda Y Davydova, James R Halpert, et al.
Physiological and Biochemical Zoology : PBZ|September 3, 2013
An in vivo assay for elucidating the importance of cytochromes P450 for the ability of a wild mammalian herbivore (Neotoma lepida) to consume toxic plantsMichele M Skopec, Jael R Malenke, James R Halpert, et al.
ACS Chemical Biology|April 4, 2017
Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate SelectivityManish B Shah, Jingbao Liu, Qinghai Zhang, et al.
Plos One|December 31, 2013
A large-scale allosteric transition in cytochrome P450 3A4 revealed by luminescence resonance energy transfer (LRET)Elena V Sineva, Jessica A O Rumfeldt, James R Halpert, et al.
Molecular Pharmacology|August 31, 2011
Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chainsManish B Shah, Jaime Pascual, Qinghai Zhang, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 21, 2009
Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selectionSantosh Kumar, Huan Qiu, Numan Oezguen, et al.
Archives of Biochemistry and Biophysics|March 6, 2004
Mutagenesis and molecular dynamics suggest structural and functional roles for residues in the N-terminal portion of the cytochrome P450 2B1 I helixEmily E Scott, Hong Liu, You Qun He, et al.
Biochemistry|April 29, 2009
Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole: ligand-induced structural response through alpha-helical repositioningSean C Gay, Ling Sun, Keiko Maekawa, et al.
Pageof 11

Showing results (41-50 of 108) with videos related to

Sort By:
Pageof 11
Chemical Research in Toxicology|June 18, 2002
Site-directed mutagenesis of cytochrome P450eryF: implications for substrate oxidation, cooperativity, and topology of the active siteKishore K Khan, You Ai He, You Qun He, et al.
Protein Engineering, Design & Selection : PEDS|October 20, 2006
Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxideSantosh Kumar, Ling Sun, Hong Liu, et al.
Biochemistry|January 3, 2007
Mechanism of interactions of alpha-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probeTamara N Tsalkova, Nadezhda Y Davydova, James R Halpert, et al.
Physiological and Biochemical Zoology : PBZ|September 3, 2013
An in vivo assay for elucidating the importance of cytochromes P450 for the ability of a wild mammalian herbivore (Neotoma lepida) to consume toxic plantsMichele M Skopec, Jael R Malenke, James R Halpert, et al.
ACS Chemical Biology|April 4, 2017
Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate SelectivityManish B Shah, Jingbao Liu, Qinghai Zhang, et al.
Plos One|December 31, 2013
A large-scale allosteric transition in cytochrome P450 3A4 revealed by luminescence resonance energy transfer (LRET)Elena V Sineva, Jessica A O Rumfeldt, James R Halpert, et al.
Molecular Pharmacology|August 31, 2011
Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chainsManish B Shah, Jaime Pascual, Qinghai Zhang, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 21, 2009
Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selectionSantosh Kumar, Huan Qiu, Numan Oezguen, et al.
Archives of Biochemistry and Biophysics|March 6, 2004
Mutagenesis and molecular dynamics suggest structural and functional roles for residues in the N-terminal portion of the cytochrome P450 2B1 I helixEmily E Scott, Hong Liu, You Qun He, et al.
Biochemistry|April 29, 2009
Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole: ligand-induced structural response through alpha-helical repositioningSean C Gay, Ling Sun, Keiko Maekawa, et al.
Pageof 11