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James R Halpert

Showing results (51-60 of 108) with videos related to

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Biochemical and Biophysical Research Communications|November 25, 2003
Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopyDmitri R Davydov, James R Halpert, Jean-Paul Renaud, et al.
The Journal of Biological Chemistry|January 28, 2006
Conformational flexibility of mammalian cytochrome P450 2B4 in binding imidazole inhibitors with different ring chemistry and side chains. Solution thermodynamics and molecular modelingB K Muralidhara, Surendra Negi, Christopher C Chin, et al.
Biophysical Journal|April 14, 2016
Conformational Mobility in Cytochrome P450 3A4 Explored by Pressure-Perturbation EPR SpectroscopyDmitri R Davydov, Zhongyu Yang, Nadezhda Davydova, et al.
The Journal of Biological Chemistry|May 23, 2008
Identification and analysis of conserved sequence motifs in cytochrome P450 family 2. Functional and structural role of a motif 187RFDYKD192 in CYP2B enzymesNuman Oezguen, Santosh Kumar, Aditya Hindupur, et al.
Biochemistry|May 26, 2004
An electrostatically driven conformational transition is involved in the mechanisms of substrate binding and cooperativity in cytochrome P450eryFDmitri R Davydov, Alexandra E Botchkareva, Santosh Kumar, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 8, 2004
Topological changes in the CYP3A4 active site probed with phenyldiazene: effect of interaction with NADPH-cytochrome P450 reductase and cytochrome b5 and of site-directed mutagenesisYoshitaka Yamaguchi, Kishore K Khan, You Ai He, et al.
Archives of Biochemistry and Biophysics|January 9, 2013
X-ray crystal structure of the cytochrome P450 2B4 active site mutant F297A in complex with clopidogrel: insights into compensatory rearrangements of the binding pocketManish B Shah, Hyun-Hee Jang, Qinghai Zhang, et al.
The Biochemical Journal|May 9, 2013
Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavoneDmitri R Davydov, Nadezhda Y Davydova, Elena V Sineva, et al.
Archives of Biochemistry and Biophysics|August 31, 2015
Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymesHyun-Hee Jang, Jingbao Liu, Ga-Young Lee, et al.
The Journal of Pharmacology and Experimental Therapeutics|December 20, 2002
Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modelingMargit Spatzenegger, Hong Liu, Qinmi Wang, et al.
Pageof 11

Showing results (51-60 of 108) with videos related to

Sort By:
Pageof 11
Biochemical and Biophysical Research Communications|November 25, 2003
Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopyDmitri R Davydov, James R Halpert, Jean-Paul Renaud, et al.
The Journal of Biological Chemistry|January 28, 2006
Conformational flexibility of mammalian cytochrome P450 2B4 in binding imidazole inhibitors with different ring chemistry and side chains. Solution thermodynamics and molecular modelingB K Muralidhara, Surendra Negi, Christopher C Chin, et al.
Biophysical Journal|April 14, 2016
Conformational Mobility in Cytochrome P450 3A4 Explored by Pressure-Perturbation EPR SpectroscopyDmitri R Davydov, Zhongyu Yang, Nadezhda Davydova, et al.
The Journal of Biological Chemistry|May 23, 2008
Identification and analysis of conserved sequence motifs in cytochrome P450 family 2. Functional and structural role of a motif 187RFDYKD192 in CYP2B enzymesNuman Oezguen, Santosh Kumar, Aditya Hindupur, et al.
Biochemistry|May 26, 2004
An electrostatically driven conformational transition is involved in the mechanisms of substrate binding and cooperativity in cytochrome P450eryFDmitri R Davydov, Alexandra E Botchkareva, Santosh Kumar, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 8, 2004
Topological changes in the CYP3A4 active site probed with phenyldiazene: effect of interaction with NADPH-cytochrome P450 reductase and cytochrome b5 and of site-directed mutagenesisYoshitaka Yamaguchi, Kishore K Khan, You Ai He, et al.
Archives of Biochemistry and Biophysics|January 9, 2013
X-ray crystal structure of the cytochrome P450 2B4 active site mutant F297A in complex with clopidogrel: insights into compensatory rearrangements of the binding pocketManish B Shah, Hyun-Hee Jang, Qinghai Zhang, et al.
The Biochemical Journal|May 9, 2013
Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavoneDmitri R Davydov, Nadezhda Y Davydova, Elena V Sineva, et al.
Archives of Biochemistry and Biophysics|August 31, 2015
Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymesHyun-Hee Jang, Jingbao Liu, Ga-Young Lee, et al.
The Journal of Pharmacology and Experimental Therapeutics|December 20, 2002
Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modelingMargit Spatzenegger, Hong Liu, Qinmi Wang, et al.
Pageof 11