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Plos Medicine|December 7, 2016
Sequencing Strategies to Guide Decision Making in Cancer TreatmentJames T Topham, Marco A MarraTherapeutic Advances in Medical Oncology|March 10, 2023
Circulating tumor DNA: toward evolving the clinical paradigm of pancreatic ductal adenocarcinomaJames T Topham, Daniel J Renouf, David F SchaefferJCO Precision Oncology|August 23, 2024
Kinetic Profiling of <i>RAS</i> Mutations With Circulating Tumor DNA in the Canadian Cancer Trials Group CO.26 Trial Suggests the Loss of <i>RAS</i> Mutations in Neo-<i>RAS</i>-Wildtype Metastatic Colorectal Cancer Is TransientFlorence T H Wu, James T Topham, Chris J O'Callaghan, et al.Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology|August 25, 2022
Circulating Tumor DNA Identifies Diverse Landscape of Acquired Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal CancerJames T Topham, Chris J O'Callaghan, Harriet Feilotter, et al.NPJ Precision Oncology|March 4, 2025
Whole-genome analysis of an aggressive metastatic pancreatic solid pseudopapillary neoplasmPhoebe T M Cheng, James T Topham, Ayman Aldeheshi, et al.International Journal of Cancer|September 21, 2020
Stroma vs epithelium-enhanced prognostics through histologic stratification in pancreatic ductal adenocarcinomaSteve E Kalloger, Joanna M Karasinska, Martin S Keung, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 10, 2024
Plasma versus Tissue Tumor Mutational Burden as Biomarkers of Durvalumab plus Tremelimumab Response in Patients with Metastatic Colorectal Cancer in the CO.26 TrialJonathan M Loree, Emma Titmuss, James T Topham, et al.Nucleic Acids Research|October 2, 2025
KRAS-induced STN1 (OBFC1) promotes proper CTC1-STN1-TEN1 complex-independent DNA double-strand break repair and cell cycle checkpoint maintenance in pancreatic cancerChangxian Shen, Tiantian Cui, Linlin Yang, et al.The Journal of Molecular Diagnostics : JMD|April 3, 2022
The Neoantigen Landscape of the Coding and Noncoding Cancer Genome SpaceTammy T Y Lau, Zahra J Sefid Dashti, Emma Titmuss, et al.Cancer & Metabolism|October 4, 2024
Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profilesHassan A Ali, Joanna M Karasinska, James T Topham, et al.Pageof 4