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Cancer Medicine|December 29, 2020
Tumor infiltrating neutrophils and gland formation predict overall survival and molecular subgroups in pancreatic ductal adenocarcinomaJulia R Naso, James T Topham, Joanna M Karasinska, et al.
Therapeutic Advances in Medical Oncology|June 30, 2023
Optimizing the number of variants tracked to follow disease burden with circulating tumor DNA assays in metastatic colorectal cancerMélina Boutin, James T Topham, Harriet Feilotter, et al.
Communications Biology|July 4, 2025
Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasisPaul C McDonald, James T Topham, Shannon Awrey, et al.
Journal of the National Cancer Institute|May 18, 2023
Feasibility and value of genomic profiling in cancer of unknown primary: real-world evidence from prospective profiling studyRyan W Huey, Aakash Tushar Shah, Honey V Reddi, et al.
Science Advances|March 1, 2024
Nutrient scavenging-fueled growth in pancreatic cancer depends on caveolae-mediated endocytosis under nutrient-deprived conditionsAdam R Wolfe, Tiantian Cui, Sooin Baie, et al.
NPJ Precision Oncology|March 25, 2023
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy durationErica S Tsang, Veronika Csizmok, Laura M Williamson, et al.
Gastroenterology|May 13, 2019
Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to HypoxiaPaul C McDonald, Shawn C Chafe, Wells S Brown, et al.
Gut|September 16, 2020
Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinomaRobert C Grant, Robert Denroche, Gun Ho Jang, et al.
Nature Communications|August 26, 2022
The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinomaDaniel J Renouf, Jonathan M Loree, Jennifer J Knox, et al.
Nature Communications|March 7, 2026
DNA Repair gene alterations and efficacy from gemcitabine and nab-paclitaxel with/without durvalumab and tremelimumab in metastatic pancreatic ductal adenocarcinomaDaniel J Renouf, James T Topham, Jonathan M Loree, et al.
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