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Journal of Medicinal Chemistry|December 22, 2020
Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 InhibitorsChristine Brotherton-Pleiss, Peibin Yue, Yinsong Zhu, et al.Cancer Research|August 21, 2020
STAT3 and GR Cooperate to Drive Gene Expression and Growth of Basal-Like Triple-Negative Breast CancerMegan E Conway, Joy M McDaniel, James M Graham, et al.Oncogene|April 18, 2002
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesisGuilian Niu, Kenneth L Wright, Mei Huang, et al.Journal of Medicinal Chemistry|September 3, 2015
Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin α-2 Expression, and Induce Antitumor Effects against Human GliomaGabriella Miklossy, Ui Joung Youn, Peibin Yue, et al.Redox Biology|April 28, 2022
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancerShumin Ouyang, Huaxuan Li, Linlin Lou, et al.Cancer Research|December 17, 2008
The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies?Joelle Hillion, Surajit Dhara, Takita Felder Sumter, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|January 7, 2006
Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cellsTanya Gritsko, Ann Williams, James Turkson, et al.Molecular Cancer Research : MCR|February 6, 2020
27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6-JAK-STAT3 Signaling in Prostate Cancer CellsShweta Dambal, Mahmoud Alfaqih, Sergio Sanders, et al.Cancer Letters|March 11, 2022
Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivoPeibin Yue, Yinsong Zhu, Christine Brotherton-Pleiss, et al.Cell Death and Differentiation|October 17, 2018
Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicineMichele Carbone, Ivano Amelio, El Bachir Affar, et al.Pageof 9