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Cancer Research|October 30, 2025
RAS-GTP Inhibition Overcomes Acquired Resistance to KRASG12C Inhibitors Mediated by Oncogenic and Wildtype RAS Activation in Non-Small Cell Lung CancerHitendra S Solanki, Harshit Shah, Denis Imbody, et al.Nature Chemical Biology|June 25, 2021
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growthBianca J Lee, Jacob A Boyer, G Leslie Burnett, et al.Stroke|December 15, 2020
Thrombus Migration and Fragmentation After Intravenous Alteplase Treatment: The INTERRSeCT StudyTomoyuki Ohara, Bijoy K Menon, Fahad S Al-Ajlan, et al.Cancer Cell|April 24, 2026
Anticancer activity of RAS-GTP inhibition in cholangiocarcinomaRodrigo Entrialgo-Cadierno, Konstantina Morali, Iker Feliu, et al.Journal of Medicinal Chemistry|December 19, 2022
Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated TumorsG Leslie Burnett, Yu C Yang, James B Aggen, et al.Cancer Discovery|April 9, 2024
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven CancersJingjing Jiang, Lingyan Jiang, Benjamin J Maldonato, et al.Cancer Discovery|February 11, 2026
Abrogation of Oncogenic RAS Signaling by a RAS(ON) Inhibitor Doublet Primes Immune-refractory KRAS G12C-mutant NSCLC for Immune Checkpoint BlockadeXing Wei, Cristina Blaj, M Ali Al-Radhawi, et al.Nature|April 8, 2024
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapyMatthew Holderfield, Bianca J Lee, Jingjing Jiang, et al.Pageof 9