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Science Advances|November 5, 2020
Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen speciesHyewon Kong, Colleen R Reczek, Gregory S McElroy, et al.Iscience|May 18, 2020
A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human CellsG Jordan Ray, Elizabeth A Boydston, Emily Shortt, et al.Molecular Cell|October 8, 2013
The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1Zhi-Yang Tsun, Liron Bar-Peled, Lynne Chantranupong, et al.Science (New York, N.Y.)|October 10, 2015
Sestrin2 is a leucine sensor for the mTORC1 pathwayRachel L Wolfson, Lynne Chantranupong, Robert A Saxton, et al.Journal of Medicinal Chemistry|February 17, 2011
Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancerQingsong Liu, Jinhua Wang, Seong A Kang, et al.Cell|April 8, 2017
Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP SynthaseJason R Cantor, Monther Abu-Remaileh, Naama Kanarek, et al.Science (New York, N.Y.)|May 24, 2008
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1Yasemin Sancak, Timothy R Peterson, Yoav D Shaul, et al.Proceedings of the National Academy of Sciences of the United States of America|August 20, 2024
Rag-Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathwayMax L Valenstein, Pranav V Lalgudi, Xin Gu, et al.Nucleic Acids Research|December 3, 2015
MERAV: a tool for comparing gene expression across human tissues and cell typesYoav D Shaul, Bingbing Yuan, Prathapan Thiru, et al.American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons|July 4, 2018
DEPTOR modulates activation responses in CD4+ T cells and enhances immunoregulation following transplantationJohannes Wedel, Sarah Bruneau, Kaifeng Liu, et al.Pageof 25