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Nature Chemical Biology|October 24, 2017
A CRISPR screen identifies a pathway required for paraquat-induced cell deathColleen R Reczek, Kıvanç Birsoy, Hyewon Kong, et al.Analytical Chemistry|July 10, 2010
Native capillary isoelectric focusing for the separation of protein complex isoforms and subcomplexesBryan R Fonslow, Seong A Kang, Daniel R Gestaut, et al.Nature|December 25, 2012
Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survivalAlejo Efeyan, Roberto Zoncu, Steven Chang, et al.Molecular Metabolism|February 25, 2016
Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesityAlexandre Caron, Sébastien M Labbé, Damien Lanfray, et al.Science (New York, N.Y.)|October 17, 2015
Identification and characterization of essential genes in the human genomeTim Wang, Kıvanç Birsoy, Nicholas W Hughes, et al.Science (New York, N.Y.)|October 28, 2017
Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomesMonther Abu-Remaileh, Gregory A Wyant, Choah Kim, et al.Cell Metabolism|March 2, 2021
CRISPR screens in physiologic medium reveal conditionally essential genes in human cellsNicholas J Rossiter, Kimberly S Huggler, Charles H Adelmann, et al.Cancer Discovery|March 18, 2014
A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivityBrian C Grabiner, Valentina Nardi, Kıvanc Birsoy, et al.Proceedings of the National Academy of Sciences of the United States of America|May 11, 2019
Activation of PASK by mTORC1 is required for the onset of the terminal differentiation programChintan K Kikani, Xiaoying Wu, Sarah Fogarty, et al.Science (New York, N.Y.)|November 21, 2015
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathwayRobert A Saxton, Kevin E Knockenhauer, Rachel L Wolfson, et al.Pageof 25