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Chemmedchem|August 26, 2009
Design and synthesis of a series of piperazine-1-carboxamidine derivatives with antifungal activity resulting from accumulation of endogenous reactive oxygen speciesIsabelle E François, Karin Thevissen, Klaartje Pellens, et al.Drugs in R&D|September 11, 2004
Correlations between factors determining the pharmacokinetics and antiviral activity of HIV-1 non-nucleoside reverse transcriptase inhibitors of the diaryltriazine and diarylpyrimidine classes of compoundsPaul Lewi, Eddy Arnold, Koen Andries, et al.Journal of Computer-Aided Molecular Design|September 19, 2003
On the detection of multiple-binding modes of ligands to proteins, from biological, structural, and modeling dataPaul J Lewi, Marc de Jonge, Frits Daeyaert, et al.Journal of Medicinal Chemistry|March 18, 2005
Synthesis of novel diarylpyrimidine analogues and their antiviral activity against human immunodeficiency virus type 1Jerome Guillemont, Elisabeth Pasquier, Patrice Palandjian, et al.Journal of Medicinal Chemistry|March 18, 2005
Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activityJan Heeres, Marc R de Jonge, Lucien M H Koymans, et al.Journal of Medicinal Chemistry|March 18, 2005
Synthesis and in vitro and in vivo structure-activity relationships of novel antifungal triazoles for dermatologyLieven Meerpoel, Leo J J Backx, Louis J E Van der Veken, et al.Journal of Medicinal Chemistry|March 18, 2005
In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine)Paul A J Janssen, Paul J Lewi, Eddy Arnold, et al.Journal of Medicinal Chemistry|April 30, 2004
Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variantsKalyan Das, Arthur D Clark, Paul J Lewi, et al.Chemmedchem|April 10, 2010
Synthesis and in vitro and in vivo antifungal activity of the hydroxy metabolites of saperconazoleLieven Meerpoel, Jan Heeres, Leo J J Backx, et al.Pageof 4