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Analytical and Bioanalytical Chemistry|January 13, 2016
Application of a cocktail approach to screen cytochrome P450 BM3 libraries for metabolic activity and diversityJelle Reinen, Geert Postma, Cornelis Tump, et al.
Bioorganic & Medicinal Chemistry|July 8, 2014
Application of engineered cytochrome P450 mutants as biocatalysts for the synthesis of benzylic and aromatic metabolites of fenamic acid NSAIDsHarini Venkataraman, Marlies C A Verkade-Vreeker, Luigi Capoferri, et al.
Applied Microbiology and Biotechnology|December 17, 2014
Biosynthesis of a steroid metabolite by an engineered Rhodococcus erythropolis strain expressing a mutant cytochrome P450 BM3 enzymeHarini Venkataraman, Evelien M Te Poele, Kamila Z Rosłoniec, et al.
Journal of Molecular Graphics & Modelling|June 12, 2003
Modeling and molecular dynamics of glutamine transaminase K/cysteine conjugate beta-lyaseJennifer Venhorst, Antonius M ter Laak, Moira Meijer, et al.
Chemical Research in Toxicology|September 26, 2008
Trimethoprim: novel reactive intermediates and bioactivation pathways by cytochrome p450sMicaela C Damsten, Jon S B de Vlieger, Wilfried M A Niessen, et al.
Archives of Toxicology|March 7, 2014
A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studiesSreenivasa C Ramaiahgari, Michiel W den Braver, Bram Herpers, et al.
Chemical Research in Toxicology|February 21, 2014
Human NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated inactivation of reactive quinoneimine metabolites of diclofenac and mefenamic acidGalvin Vredenburg, Naura S Elias, Harini Venkataraman, et al.
Drug Metabolism Letters|April 10, 2009
In vitro metabolism studies of new adenosine A 2A receptor antagonistsGabriella Marucci, Sara Finaurini, Michela Buccioni, et al.
Plos One|November 10, 2015
Linear Interaction Energy Based Prediction of Cytochrome P450 1A2 Binding Affinities with Reliability EstimationLuigi Capoferri, Marlies C A Verkade-Vreeker, Danny Buitenhuis, et al.
Biochemical Pharmacology|October 23, 2004
Influence of phenylalanine 120 on cytochrome P450 2D6 catalytic selectivity and regiospecificity: crucial role in 7-methoxy-4-(aminomethyl)-coumarin metabolismPeter H J Keizers, Barbara M A Lussenburg, Chris de Graaf, et al.
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