Jan N M Commandeur - JoVE Visualize

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Environmental Toxicology and Pharmacology|July 26, 2011

The use of in vitro metabolic parameters and physiologically based pharmacokinetic (PBPK) modeling to explore the risk assessment of trichloroethyleneErna M Hissink, Jan J P Bogaards, Andreas P Freidig, et al.

Toxicology in Vitro : an International Journal Published in Association with BIBRA|February 28, 2016

Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayerShalenie P den Braver-Sewradj, Michiel W den Braver, Nico P E Vermeulen, et al.

Biochemical and Biophysical Research Communications|March 28, 2006

Binding of bufuralol, dextromethorphan, and 3,4-methylenedioxymethylamphetamine to wild-type and F120A mutant cytochrome P450 2D6 studied by resonance Raman spectroscopyAlois Bonifacio, Peter H J Keizers, Jan N M Commandeur, et al.

Plos One|May 25, 2019

Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitolKarla Frydenvang, Marlies C A Verkade-Vreeker, Floor Dohmen, et al.

European Biophysics Journal : EBJ|March 3, 2007

Free energies of binding of R- and S-propranolol to wild-type and F483A mutant cytochrome P450 2D6 from molecular dynamics simulationsChris de Graaf, Chris Oostenbrink, Peter H J Keizers, et al.

Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|September 11, 2007

Cytochrome P450 bio-affinity detection coupled to gradient HPLC: on-line screening of affinities to cytochrome P4501A2 and 2D6Jeroen Kool, Sebastiaan M van Liempd, Stefan Harmsen, et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 26, 2007

Development of three parallel cytochrome P450 enzyme affinity detection systems coupled on-line to gradient high-performance liquid chromatographyJeroen Kool, Sebastiaan M van Liempd, Huub van Rossum, et al.

Toxicology Letters|December 3, 2014

Activation of the anticancer drugs cyclophosphamide and ifosfamide by cytochrome P450 BM3 mutantsGalvin Vredenburg, Shalenie den Braver-Sewradj, Barbara M A van Vugt-Lussenburg, et al.

Biochemical Pharmacology|May 30, 2002

Induction of glutathione-S-transferase mRNA levels by chemopreventive selenocysteine Se-conjugatesPeter A C 't Hoen, Martijn Rooseboom, Martin K Bijsterbosch, et al.

Chemico-Biological Interactions|November 13, 2007

Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolitesMicaela C Damsten, Barbara M A van Vugt-Lussenburg, Tineke Zeldenthuis, et al.

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Showing results (61-70 of 98) with videos related to

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Pageof 10

Environmental Toxicology and Pharmacology|July 26, 2011

The use of in vitro metabolic parameters and physiologically based pharmacokinetic (PBPK) modeling to explore the risk assessment of trichloroethyleneErna M Hissink, Jan J P Bogaards, Andreas P Freidig, et al.

Toxicology in Vitro : an International Journal Published in Association with BIBRA|February 28, 2016

Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayerShalenie P den Braver-Sewradj, Michiel W den Braver, Nico P E Vermeulen, et al.

Biochemical and Biophysical Research Communications|March 28, 2006

Binding of bufuralol, dextromethorphan, and 3,4-methylenedioxymethylamphetamine to wild-type and F120A mutant cytochrome P450 2D6 studied by resonance Raman spectroscopyAlois Bonifacio, Peter H J Keizers, Jan N M Commandeur, et al.

Plos One|May 25, 2019

Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitolKarla Frydenvang, Marlies C A Verkade-Vreeker, Floor Dohmen, et al.

European Biophysics Journal : EBJ|March 3, 2007

Free energies of binding of R- and S-propranolol to wild-type and F483A mutant cytochrome P450 2D6 from molecular dynamics simulationsChris de Graaf, Chris Oostenbrink, Peter H J Keizers, et al.

Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|September 11, 2007

Cytochrome P450 bio-affinity detection coupled to gradient HPLC: on-line screening of affinities to cytochrome P4501A2 and 2D6Jeroen Kool, Sebastiaan M van Liempd, Stefan Harmsen, et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 26, 2007

Development of three parallel cytochrome P450 enzyme affinity detection systems coupled on-line to gradient high-performance liquid chromatographyJeroen Kool, Sebastiaan M van Liempd, Huub van Rossum, et al.

Toxicology Letters|December 3, 2014

Activation of the anticancer drugs cyclophosphamide and ifosfamide by cytochrome P450 BM3 mutantsGalvin Vredenburg, Shalenie den Braver-Sewradj, Barbara M A van Vugt-Lussenburg, et al.

Biochemical Pharmacology|May 30, 2002

Induction of glutathione-S-transferase mRNA levels by chemopreventive selenocysteine Se-conjugatesPeter A C 't Hoen, Martijn Rooseboom, Martin K Bijsterbosch, et al.

Chemico-Biological Interactions|November 13, 2007

Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolitesMicaela C Damsten, Barbara M A van Vugt-Lussenburg, Tineke Zeldenthuis, et al.

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