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Journal of Biomolecular Screening|August 12, 2005
Development of a novel cytochrome p450 bioaffinity detection system coupled online to gradient reversed-phase high-performance liquid chromatographyJeroen Kool, Sebastiaan M van Liempd, Rawi Ramautar, et al.Biochemical Pharmacology|September 2, 2005
The role of phenylalanine 483 in cytochrome P450 2D6 is strongly substrate dependentBarbara M A Lussenburg, Peter H J Keizers, Chris de Graaf, et al.Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry|September 28, 2007
Active-site structure, binding and redox activity of the heme-thiolate enzyme CYP2D6 immobilized on coated Ag electrodes: a surface-enhanced resonance Raman scattering studyAlois Bonifacio, Diego Millo, Peter H J Keizers, et al.Archives of Toxicology|August 24, 2012
AMAP, the alleged non-toxic isomer of acetaminophen, is toxic in rat and human liverMackenzie Hadi, Sanja Dragovic, Rachel van Swelm, et al.Journal of Medicinal Chemistry|September 16, 2005
Metabolic regio- and stereoselectivity of cytochrome P450 2D6 towards 3,4-methylenedioxy-N-alkylamphetamines: in silico predictions and experimental validationPeter H J Keizers, Chris de Graaf, Frans J J de Kanter, et al.Chembiochem : a European Journal of Chemical Biology|January 26, 2012
A single active site mutation inverts stereoselectivity of 16-hydroxylation of testosterone catalyzed by engineered cytochrome P450 BM3Harini Venkataraman, Stephanie B A de Beer, Laura A H van Bergen, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 16, 2011
Efficient screening of cytochrome P450 BM3 mutants for their metabolic activity and diversity toward a wide set of drug-like molecules in chemical spaceJelle Reinen, Jolanda S van Leeuwen, Yongmin Li, et al.Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|October 5, 2007
Automated detection of covalent adducts to human serum albumin by immunoaffinity chromatography, on-line solution phase digestion and liquid chromatography-mass spectrometryJohannes S Hoos, Micaela C Damsten, Jon S B de Vlieger, et al.Applied Microbiology and Biotechnology|August 24, 2018
Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partnersSandra Ortega Ugalde, Coen P de Koning, Kerstin Wallraven, et al.Biochemical and Biophysical Research Communications|November 5, 2005
Role of the conserved threonine 309 in mechanism of oxidation by cytochrome P450 2D6Peter H J Keizers, Loek H M Schraven, Chris de Graaf, et al.Pageof 10