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International Journal of Toxicology|June 17, 2021
Nonclinical Safety Profile of Sotorasib, a KRASG12C-Specific Covalent Inhibitor for the Treatment of KRAS p.G12C-Mutated CancerKatsu Ishida, Jonathan A Werner, Rhian Davies, et al.Clinical and Translational Science|November 12, 2022
Evaluation of levocetirizine in beagle dog and cynomolgus monkey telemetry assays: Defining the no QTc effect profile by timepoint and concentration-QTc analysisMichael J Engwall, Joel Baublits, Fiona A Chandra, et al.The AAPS Journal|February 28, 2025
Considerations in Kp,uu,brain-based Strategy for Selecting CNS-targeted Drug Candidates with Sufficient Target Coverage and Substantial Pharmacodynamic EffectLing Zou, Huan-Chieh Chien, Devendra Pade, et al.Clinical and Translational Science|August 20, 2021
Evaluation of drug-drug interaction potential between omecamtiv mecarbil and rosuvastatin, a BCRP substrate, with a clinical study in healthy subjects and using a physiologically-based pharmacokinetic modelAshit Trivedi, Winnie Sohn, Priyanka Kulkarni, et al.Journal of Immunology (Baltimore, Md. : 1950)|April 6, 2006
Allergen-specific MHC class II tetramer+ cells are detectable in allergic, but not in nonallergic, individualsClaudia Macaubas, Jan Wahlstrom, Ana Paula Galvão da Silva, et al.Biochemical and Biophysical Research Communications|June 24, 2026
Rapid screening approaches to identify and confirm lysosomotropic agents among ECCS class 2 basic drugsOsatohanmwen J Enogieru, Minhkhoi Nguyen, Ling Zou, et al.Journal of Pharmaceutical Sciences|February 3, 2015
Utilizing physiologically based pharmacokinetic modeling to inform formulation and clinical development for a compound with pH-dependent solubilityJohn Chung, Fernando Alvarez-Nunez, Vincent Chow, et al.Toxicology and Applied Pharmacology|May 18, 2021
Mercapturate pathway metabolites of sotorasib, a covalent inhibitor of KRASG12C, are associated with renal toxicity in the Sprague Dawley ratJonathan A Werner, Rhian Davies, Jan Wahlstrom, et al.Regenerative Medicine|May 19, 2012
Disclosure and management of research findings in stem cell research and banking: policy statementRosario Isasi, Bartha M Knoppers, Peter W Andrews, et al.Genomics|February 28, 2002
Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism mapDuncan Hewett, Lena Samuelsson, Joanne Polding, et al.Pageof 3