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Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology|May 8, 2013
Randomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal aromatase inhibitorDenise A Yardley, Roohi R Ismail-Khan, Bohuslav Melichar, et al.The Journal of Biological Chemistry|March 20, 2009
Inhibition of tumor cell motility by the interferon-inducible GTPase MxAJ Frederic Mushinski, Phuongmai Nguyen, Lisa M Stevens, et al.Journal of Immunology (Baltimore, Md. : 1950)|December 22, 2007
Ex vivo rapamycin generates apoptosis-resistant donor Th2 cells that persist in vivo and prevent hemopoietic stem cell graft rejectionJacopo Mariotti, Jason Foley, Unsu Jung, et al.Cancer Biology & Therapy|August 19, 2008
Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancerXu-Hui Zhang, Mahadev Rao, Joseph A Loprieato, et al.Journal of Clinical Pharmacology|December 5, 2015
UGT1A1 genotype-dependent dose adjustment of belinostat in patients with advanced cancers using population pharmacokinetic modeling and simulationCody J Peer, Andrew K L Goey, Tristan M Sissung, et al.Molecular Cancer Therapeutics|June 24, 2004
Aryl hydrocarbon receptor activation of an antitumor aminoflavone: basis of selective toxicity for MCF-7 breast tumor cellsAndrea I Loaiza-Pérez, Susan Kenney, Jamie Boswell, et al.Scientific Reports|May 5, 2018
HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulationToshiki Kijima, Thomas L Prince, Megan L Tigue, et al.Nature Communications|June 14, 2019
Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1Wanping Xu, Kristin Beebe, Juan D Chavez, et al.Molecular Cell|June 26, 2012
Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machineWanping Xu, Mehdi Mollapour, Chrisostomos Prodromou, et al.Plos One|October 31, 2015
Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted MutantsThomas L Prince, Toshiki Kijima, Manabu Tatokoro, et al.Pageof 14