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The Journal of Pain|August 4, 2026
Drug-opposite neuroadaptation and breakthrough painJane C Ballantyne, George F KoobPharmacological Reviews|December 15, 2020
Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications DevelopmentGeorge F KoobCurrent Topics in Behavioral Neurosciences|February 3, 2022
Anhedonia, Hyperkatifeia, and Negative Reinforcement in Substance Use DisordersGeorge F KoobNeuropharmacology|August 30, 2008
Neurobiological substrates for the dark side of compulsivity in addictionGeorge F KoobFrontiers in Psychiatry|August 6, 2013
Addiction is a Reward Deficit and Stress Surfeit DisorderGeorge F KoobCurrent Opinion in Neurobiology|May 1, 2013
Negative reinforcement in drug addiction: the darkness withinGeorge F KoobHandbook of Clinical Neurology|October 14, 2014
Neurocircuitry of alcohol addiction: synthesis from animal modelsGeorge F KoobEuropean Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology|November 26, 2003
Neuroadaptive mechanisms of addiction: studies on the extended amygdalaGeorge F KoobBiochemical Pharmacology|September 29, 2004
A role for GABA mechanisms in the motivational effects of alcoholGeorge F KoobPageof 39