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Nature|April 8, 2026
DNA damage drives antigen diversification in Trypanosoma bruceiJaclyn E Smith, Kevin J Wang, Erin M Kennedy, et al.The Journal of Antimicrobial Chemotherapy|December 21, 2019
Evaluation of phthalazinone phosphodiesterase inhibitors with improved activity and selectivity against Trypanosoma cruziJulianna Siciliano De Araújo, Patrícia Bernardino da Silva, Marcos Meuser Batista, et al.The Journal of Antimicrobial Chemotherapy|November 16, 2013
Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugsJane C Munday, Anthonius A Eze, Nicola Baker, et al.International Journal for Parasitology. Drugs and Drug Resistance|January 23, 2019
Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activitySanaa S Botros, Samia William, Abdel-Nasser A Sabra, et al.Journal of Medicinal Chemistry|April 20, 2018
Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal ActivityAntoni R Blaazer, Abhimanyu K Singh, Erik de Heuvel, et al.Elife|August 9, 2020
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma bruceiAli H Alghamdi, Jane C Munday, Gustavo Daniel Campagnaro, et al.Pageof 3