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Plos Computational Biology
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February 5, 2024
Index analysis: An approach to understand signal transduction with application to the EGFR signalling pathway
Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga
Journal of Pharmacokinetics and Pharmacodynamics
|
December 16, 2017
Understanding and reducing complex systems pharmacology models based on a novel input-response index
Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga
CPT: Pharmacometrics & Systems Pharmacology
|
January 22, 2026
Tackling High Dimensionality in QSP: Guiding Model Order Reduction With Index Analysis
Johannes Tillil, Wilhelm Huisinga, Jane Knöchel
CPT: Pharmacometrics & Systems Pharmacology
|
March 3, 2023
Deriving mechanism-based pharmacodynamic models by reducing quantitative systems pharmacology models: An application to warfarin
Undine Falkenhagen, Jane Knöchel, Charlotte Kloft, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
November 18, 2024
Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women
Priya Jayachandran, Jane Knöchel, Brian Cicali, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
August 19, 2024
Enhancing inclusivity in clinical trials: Model-informed drug development for pregnant individuals in the era of personalized medicine
André Dallmann, Peter L Bonate, Janelle Burnham, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
November 18, 2025
The Advance of In Silico Evidence to Transform Pediatric Drug Development for Rare Diseases
Jane Knöchel, Ping Zhao, Rajat Desikan, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
August 5, 2025
A Case Study of Model-Informed Drug Development of a Novel PCSK9 Antisense Oligonucleotide. Part 2: Phase 2 to Phase 3
Jane Knöchel, Catarina Nilsson, Björn Carlsson, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
August 4, 2025
Transforming Pediatric Rare Disease Drug Development: Enhancing Clinical Trials and Regulatory Evidence With Virtual Patients
Fianne Sips, Marco Virgolin, Giuseppe Pasculli, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
September 26, 2023
A Markov model of fibrosis development in nonalcoholic fatty liver disease predicts fibrosis progression in clinical cohorts
Jane Knöchel, Linnéa Bergenholm, Eman Ibrahim, et al.
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of 3
Search research articles
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Showing results (1-10 of 24) with videos related to
Sort By:
Page
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Plos Computational Biology
|
February 5, 2024
Index analysis: An approach to understand signal transduction with application to the EGFR signalling pathway
Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga
Journal of Pharmacokinetics and Pharmacodynamics
|
December 16, 2017
Understanding and reducing complex systems pharmacology models based on a novel input-response index
Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga
CPT: Pharmacometrics & Systems Pharmacology
|
January 22, 2026
Tackling High Dimensionality in QSP: Guiding Model Order Reduction With Index Analysis
Johannes Tillil, Wilhelm Huisinga, Jane Knöchel
CPT: Pharmacometrics & Systems Pharmacology
|
March 3, 2023
Deriving mechanism-based pharmacodynamic models by reducing quantitative systems pharmacology models: An application to warfarin
Undine Falkenhagen, Jane Knöchel, Charlotte Kloft, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
November 18, 2024
Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women
Priya Jayachandran, Jane Knöchel, Brian Cicali, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
August 19, 2024
Enhancing inclusivity in clinical trials: Model-informed drug development for pregnant individuals in the era of personalized medicine
André Dallmann, Peter L Bonate, Janelle Burnham, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
November 18, 2025
The Advance of In Silico Evidence to Transform Pediatric Drug Development for Rare Diseases
Jane Knöchel, Ping Zhao, Rajat Desikan, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
August 5, 2025
A Case Study of Model-Informed Drug Development of a Novel PCSK9 Antisense Oligonucleotide. Part 2: Phase 2 to Phase 3
Jane Knöchel, Catarina Nilsson, Björn Carlsson, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
August 4, 2025
Transforming Pediatric Rare Disease Drug Development: Enhancing Clinical Trials and Regulatory Evidence With Virtual Patients
Fianne Sips, Marco Virgolin, Giuseppe Pasculli, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
September 26, 2023
A Markov model of fibrosis development in nonalcoholic fatty liver disease predicts fibrosis progression in clinical cohorts
Jane Knöchel, Linnéa Bergenholm, Eman Ibrahim, et al.
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of 3