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Janice L Hyatt

Showing results (1-10 of 25) with videos related to

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Chemico-Biological Interactions|November 6, 2012
Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitorsLyudmila G Tsurkan, M Jason Hatfield, Carol C Edwards, et al.
Molecular Cancer Therapeutics|September 21, 2006
Intracellular inhibition of carboxylesterases by benzil: modulation of CPT-11 cytotoxicityJanice L Hyatt, Lyudmila Tsurkan, Monika Wierdl, et al.
Chemistry & Biology|May 3, 2003
Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibitionSompop Bencharit, Christopher L Morton, Janice L Hyatt, et al.
Journal of Medicinal Chemistry|June 19, 2009
Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan; CPT-11) toxicityLatorya D Hicks, Janice L Hyatt, Shana Stoddard, et al.
Molecular Cancer Therapeutics|August 10, 2004
Characterization of inhibitors of specific carboxylesterases: development of carboxylesterase inhibitors for translational applicationKyoung Jin P Yoon, Janice L Hyatt, Christopher L Morton, et al.
Journal of Medicinal Chemistry|January 5, 2008
Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrugBenjamin L Barthel, Renee C Torres, Janice L Hyatt, et al.
Journal of Natural Products|January 5, 2013
Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen")M Jason Hatfield, Lyudmila G Tsurkan, Janice L Hyatt, et al.
Chemico-Biological Interactions|November 18, 2005
The 3D structure of the anticancer prodrug CPT-11 with Torpedo californica acetylcholinesterase rationalizes its inhibitory action on AChE and its hydrolysis by butyrylcholinesterase and carboxylesteraseMichal Harel, Janice L Hyatt, Boris Brumshtein, et al.
Biochemical Pharmacology|September 14, 2010
Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11M Jason Hatfield, Lyudmila Tsurkan, Michael Garrett, et al.
Chemico-Biological Interactions|February 20, 2016
Carboxylesterases: General detoxifying enzymesM Jason Hatfield, Robyn A Umans, Janice L Hyatt, et al.
Pageof 3

Showing results (1-10 of 25) with videos related to

Sort By:
Pageof 3
Chemico-Biological Interactions|November 6, 2012
Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitorsLyudmila G Tsurkan, M Jason Hatfield, Carol C Edwards, et al.
Molecular Cancer Therapeutics|September 21, 2006
Intracellular inhibition of carboxylesterases by benzil: modulation of CPT-11 cytotoxicityJanice L Hyatt, Lyudmila Tsurkan, Monika Wierdl, et al.
Chemistry & Biology|May 3, 2003
Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibitionSompop Bencharit, Christopher L Morton, Janice L Hyatt, et al.
Journal of Medicinal Chemistry|June 19, 2009
Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan; CPT-11) toxicityLatorya D Hicks, Janice L Hyatt, Shana Stoddard, et al.
Molecular Cancer Therapeutics|August 10, 2004
Characterization of inhibitors of specific carboxylesterases: development of carboxylesterase inhibitors for translational applicationKyoung Jin P Yoon, Janice L Hyatt, Christopher L Morton, et al.
Journal of Medicinal Chemistry|January 5, 2008
Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrugBenjamin L Barthel, Renee C Torres, Janice L Hyatt, et al.
Journal of Natural Products|January 5, 2013
Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen")M Jason Hatfield, Lyudmila G Tsurkan, Janice L Hyatt, et al.
Chemico-Biological Interactions|November 18, 2005
The 3D structure of the anticancer prodrug CPT-11 with Torpedo californica acetylcholinesterase rationalizes its inhibitory action on AChE and its hydrolysis by butyrylcholinesterase and carboxylesteraseMichal Harel, Janice L Hyatt, Boris Brumshtein, et al.
Biochemical Pharmacology|September 14, 2010
Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11M Jason Hatfield, Lyudmila Tsurkan, Michael Garrett, et al.
Chemico-Biological Interactions|February 20, 2016
Carboxylesterases: General detoxifying enzymesM Jason Hatfield, Robyn A Umans, Janice L Hyatt, et al.
Pageof 3