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Journal of Molecular Biology|July 5, 2026
Clinical inflammasome biomarkers: Progress and prospectsJared R Coombs, Sabrina S Burgener, Kate SchroderImmunity|June 11, 2025
Spectosis: Dying for a complementJared R Coombs, Sabrina S Burgener, Kate SchroderCell Chemical Biology|May 17, 2024
The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axisCaroline L Holley, Stefan Emming, Mercedes M Monteleone, et al.Current Opinion in Immunology|November 12, 2020
The NLRP3 inflammasome triggers sterile neuroinflammation and Alzheimer's diseaseMark T Milner, Madhavi Maddugoda, Jürgen Götz, et al.STAR Protocols|April 25, 2022
Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analysesMark T Milner, Grace Mep Lawrence, Caroline L Holley, et al.European Journal of Immunology|February 16, 2024
Fluorochrome-labeled inhibitors of caspase-1 require membrane permeabilization to efficiently access caspase-1 in macrophagesSara J Thygesen, Sabrina S Burgener, Prerna Mudai, et al.Science Signaling|January 23, 2024
NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasomeJared R Coombs, Alina Zamoshnikova, Caroline L Holley, et al.Life Science Alliance|August 9, 2023
Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzymeAmy H Chan, Sabrina S Burgener, Kassandra Vezyrgiannis, et al.Nature Reviews. Immunology|February 20, 2010
NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?Jurg Tschopp, Kate SchroderPageof 16