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Molecular Pharmaceutics|March 26, 2016
Integrating in Silico and in Vitro Approaches To Predict Drug Accessibility to the Central Nervous SystemYan-Yan Zhang, Houfu Liu, Scott G Summerfield, et al.
Journal of Pharmaceutical Sciences|October 15, 2020
Improved Prediction of the Drug-Drug Interactions of Pemafibrate Caused by Cyclosporine A and Rifampicin via PBPK Modeling: Consideration of the Albumin-Mediated Hepatic Uptake of Pemafibrate and Inhibition Constants With Preincubation Against OATP1BJi Eun Park, Yoshihisa Shitara, Wooin Lee, et al.
Clinical and Translational Science|July 4, 2025
Pharmacokinetics of Belumosudil and Its Metabolites in Individuals With Hepatic ImpairmentOlivier Schueller, Virginie Esposito, Lauren Lohmer, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 15, 2004
Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell lineJessica B Mills, Kelly A Rose, Nalini Sadagopan, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 17, 2002
The effect of bergamottin on diazepam plasma levels and P450 enzymes in beagle dogsJasminder Sahi, Eric L Reyner, Jonathan N Bauman, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|May 25, 2011
Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytesTom De Bruyn, Zhi-Wei Ye, Annelies Peeters, et al.
British Journal of Clinical Pharmacology|March 11, 2025
Drug-drug interaction study with itraconazole supplemented with physiologically based pharmacokinetic modelling to characterize the effect of CYP3A inhibitors on venglustat pharmacokineticsLi Li, Yan-Yan Zhang, Jyoti Sharma, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|June 2, 2018
Rapid Bioavailability and Disposition protocol: A novel higher throughput approach to assess pharmacokinetics and steady-state brain distribution with reduced animal usageTingting Fu, Ruina Gao, Paul Scott-Stevens, et al.
Current Opinion in Drug Discovery & Development|February 1, 2005
In vitro ADME phenotyping in drug discovery: current challenges and future solutionsJ Andrew Williams, Jonathan Bauman, Hongliang Cai, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 19, 2003
Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibitionJasminder Sahi, Christopher B Black, Geraldine A Hamilton, et al.
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