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Jason Breed

Showing results (11-20 of 39) with videos related to

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ACS Medicinal Chemistry Letters|October 18, 2019
Building Bridges in a Series of Estrogen Receptor Degraders: An Application of Metathesis in Medicinal ChemistryJames S Scott, Jason Breed, Rodrigo J Carbajo, et al.
Nature Communications|June 15, 2019
KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobeNicolas Bery, Sandrine Legg, Judit Debreczeni, et al.
Journal of Medicinal Chemistry|October 27, 2006
N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitorLaurent F Hennequin, Jack Allen, Jason Breed, et al.
Bioorganic & Medicinal Chemistry Letters|February 21, 2012
Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitorsVibha Oza, Susan Ashwell, Patrick Brassil, et al.
Biochemistry|December 14, 2005
Prevention of MKK6-dependent activation by binding to p38alpha MAP kinaseJane E Sullivan, Geoffrey A Holdgate, Douglas Campbell, et al.
Journal of Medicinal Chemistry|May 23, 2012
Protein-ligand crystal structures can guide the design of selective inhibitors of the FGFR tyrosine kinaseRichard A Norman, Anne-Kathrin Schott, David M Andrews, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 5, 2023
Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffoldRoger Castells-Graells, Kyle Meador, Mark A Arbing, et al.
Bioorganic & Medicinal Chemistry Letters|August 28, 2003
Imidazo[1,2-a]pyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisationMalcolm Anderson, John F Beattie, Gloria A Breault, et al.
Bioorganic & Medicinal Chemistry Letters|May 3, 2005
Structure-based design of protein tyrosine phosphatase-1B inhibitorsEmma Black, Jason Breed, Alexander L Breeze, et al.
Journal of Medicinal Chemistry|January 5, 2018
Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) InhibitorsBin Yang, Melissa M Vasbinder, Alexander W Hird, et al.
Pageof 4

Showing results (11-20 of 39) with videos related to

Sort By:
Pageof 4
ACS Medicinal Chemistry Letters|October 18, 2019
Building Bridges in a Series of Estrogen Receptor Degraders: An Application of Metathesis in Medicinal ChemistryJames S Scott, Jason Breed, Rodrigo J Carbajo, et al.
Nature Communications|June 15, 2019
KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobeNicolas Bery, Sandrine Legg, Judit Debreczeni, et al.
Journal of Medicinal Chemistry|October 27, 2006
N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitorLaurent F Hennequin, Jack Allen, Jason Breed, et al.
Bioorganic & Medicinal Chemistry Letters|February 21, 2012
Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitorsVibha Oza, Susan Ashwell, Patrick Brassil, et al.
Biochemistry|December 14, 2005
Prevention of MKK6-dependent activation by binding to p38alpha MAP kinaseJane E Sullivan, Geoffrey A Holdgate, Douglas Campbell, et al.
Journal of Medicinal Chemistry|May 23, 2012
Protein-ligand crystal structures can guide the design of selective inhibitors of the FGFR tyrosine kinaseRichard A Norman, Anne-Kathrin Schott, David M Andrews, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 5, 2023
Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffoldRoger Castells-Graells, Kyle Meador, Mark A Arbing, et al.
Bioorganic & Medicinal Chemistry Letters|August 28, 2003
Imidazo[1,2-a]pyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisationMalcolm Anderson, John F Beattie, Gloria A Breault, et al.
Bioorganic & Medicinal Chemistry Letters|May 3, 2005
Structure-based design of protein tyrosine phosphatase-1B inhibitorsEmma Black, Jason Breed, Alexander L Breeze, et al.
Journal of Medicinal Chemistry|January 5, 2018
Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) InhibitorsBin Yang, Melissa M Vasbinder, Alexander W Hird, et al.
Pageof 4