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Jason Breed

Showing results (31-40 of 39) with videos related to

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Journal of Medicinal Chemistry|June 16, 2026
Discovery of CNS Penetrant SOS1 Inhibitors for the Treatment of KRAS-Dependent CancersSharan K Bagal, Coura R N Diène, Sandra Stefanovic-Barrett, et al.
Bioorganic & Medicinal Chemistry Letters|September 26, 2008
Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitorsMalcolm Anderson, David M Andrews, Andy J Barker, et al.
ACS Medicinal Chemistry Letters|August 20, 2025
Discovery of Small-Molecule Ligands for the E3 Ligase STUB1/CHIP from a DNA-Encoded Library ScreenSimon C C Lucas, Alexander G Milbradt, Jason Breed, et al.
Journal of Medicinal Chemistry|November 12, 2019
Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC)Richard A Ward, Mark J Anderton, Paul Bethel, et al.
Journal of Medicinal Chemistry|February 6, 2020
Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRAS<sup>G12C</sup>Jason G Kettle, Sharan K Bagal, Sue Bickerton, et al.
Journal of Medicinal Chemistry|April 26, 2022
Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS<sup>G12C</sup>Jason G Kettle, Sharan K Bagal, Sue Bickerton, et al.
Journal of Medicinal Chemistry|July 3, 2023
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS<sup>G12C</sup> with Demonstrable CNS PenetrationJason G Kettle, Sharan K Bagal, Derek Barratt, et al.
Journal of Medicinal Chemistry|February 2, 2023
Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-AntagonistsJames S Scott, Darren Stead, Bernard Barlaam, et al.
Journal of Medicinal Chemistry|September 10, 2020
Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and AntagonistJames S Scott, Thomas A Moss, Amber Balazs, et al.
Pageof 4

Showing results (31-40 of 39) with videos related to

Sort By:
Pageof 4
You have reached the last page of results.This site can display upto 39 results.
Journal of Medicinal Chemistry|June 16, 2026
Discovery of CNS Penetrant SOS1 Inhibitors for the Treatment of KRAS-Dependent CancersSharan K Bagal, Coura R N Diène, Sandra Stefanovic-Barrett, et al.
Bioorganic & Medicinal Chemistry Letters|September 26, 2008
Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitorsMalcolm Anderson, David M Andrews, Andy J Barker, et al.
ACS Medicinal Chemistry Letters|August 20, 2025
Discovery of Small-Molecule Ligands for the E3 Ligase STUB1/CHIP from a DNA-Encoded Library ScreenSimon C C Lucas, Alexander G Milbradt, Jason Breed, et al.
Journal of Medicinal Chemistry|November 12, 2019
Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC)Richard A Ward, Mark J Anderton, Paul Bethel, et al.
Journal of Medicinal Chemistry|February 6, 2020
Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRAS<sup>G12C</sup>Jason G Kettle, Sharan K Bagal, Sue Bickerton, et al.
Journal of Medicinal Chemistry|April 26, 2022
Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS<sup>G12C</sup>Jason G Kettle, Sharan K Bagal, Sue Bickerton, et al.
Journal of Medicinal Chemistry|July 3, 2023
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS<sup>G12C</sup> with Demonstrable CNS PenetrationJason G Kettle, Sharan K Bagal, Derek Barratt, et al.
Journal of Medicinal Chemistry|February 2, 2023
Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-AntagonistsJames S Scott, Darren Stead, Bernard Barlaam, et al.
Journal of Medicinal Chemistry|September 10, 2020
Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and AntagonistJames S Scott, Thomas A Moss, Amber Balazs, et al.
Pageof 4