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Biorxiv : the Preprint Server for Biology|October 3, 2025
FDA-approved drug repurposing in zebrafish identifies thyroid hormone and other compounds as potential antithromboticsMurat Yaman, Hongyu Su, Jacqueline K Lee, et al.
ACS Pharmacology & Translational Science|September 14, 2023
Prophylactic Mitigation of Acute Graft versus Host Disease by Novel 2-(Pyrrolidin-1-ylmethyl)pyrrole-Based Stimulation-2 (ST2) InhibitorsXinrui Yuan, Hua Jiang, Denggang Fu, et al.
ACS Medicinal Chemistry Letters|March 21, 2019
1H-Pyrrolo[3,2-b]pyridine GluN2B-Selective Negative Allosteric ModulatorsChrista C Chrovian, Akinola Soyode-Johnson, Jessica L Wall, et al.
Bioorganic & Medicinal Chemistry Letters|September 6, 2016
The discovery and preclinical characterization of 6-chloro-N-(2-(4,4-difluoropiperidin-1-yl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)quinoline-5-carboxamide based P2X7 antagonistsJason C Rech, Anindya Bhattacharya, Bryan J Branstetter, et al.
ACS Medicinal Chemistry Letters|November 20, 2024
Studies of Structure-Activity Relationship of 2-(Pyrrolidin-1ylmethyl)-1H-pyrrole-Based ST2 Inhibitors and Their Inhibition of Mast Cells ActivationXinrui Yuan, Jason C Rech, Andhavaram Ramaraju, et al.
Journal of Medicinal Chemistry|September 10, 2024
Can Machine Learning Overcome the 95% Failure Rate and Reality that Only 30% of Approved Cancer Drugs Meaningfully Extend Patient Survival?Duxin Sun, Christian Macedonia, Zhigang Chen, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 AntagonistsMichael A Letavic, Brian Lord, Francois Bischoff, et al.
Bioorganic & Medicinal Chemistry Letters|October 12, 2010
1,2-diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved propertiesAlec D Lebsack, Jason C Rech, Bryan J Branstetter, et al.
European Journal of Pharmacology|May 18, 2011
Characterization of 2-(2,6-dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine (JNJ-39729209) as a novel TRPV1 antagonistMichael P Maher, Anindya Bhattacharya, Hong Ao, et al.
Science Translational Medicine|December 3, 2020
Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiomeOren Rom, Yuhao Liu, Zhipeng Liu, et al.
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