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The Journal of Biological Chemistry|February 6, 2022
In vitro reconstitution reveals cooperative mechanisms of adapter protein-mediated activation of phospholipase C-γ1 in T cellsJunya Wada, Udumbara Rathnayake, Lisa M Jenkins, et al.
Plos One|February 22, 2020
Bypassing ubiquitination enables LAT recycling to the cell surface and enhanced signaling in T cellsLakshmi Balagopalan, Hiba Malik, Katherine M McIntire, et al.
Nature Immunology|December 13, 2016
Recruitment of calcineurin to the TCR positively regulates T cell activationDebjani Dutta, Valarie A Barr, Itoro Akpan, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 2, 2011
Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylationLakshmi Balagopalan, Benjamin A Ashwell, Kelsie M Bernot, et al.
Molecular and Cellular Biology|October 17, 2007
c-Cbl-mediated regulation of LAT-nucleated signaling complexesLakshmi Balagopalan, Valarie A Barr, Connie L Sommers, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 12, 2009
Genetic evidence for the role of Erk activation in a lymphoproliferative disease of miceMichihiko Miyaji, Robert L Kortum, Rishi Surana, et al.
The Journal of Cell Biology|October 3, 2002
T cell receptor ligation induces the formation of dynamically regulated signaling assembliesStephen C Bunnell, David I Hong, Julia R Kardon, et al.
The Journal of Experimental Medicine|July 9, 2004
Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient miceY Jeffrey Chiang, Connie L Sommers, Martha S Jordan, et al.
Nature Structural & Molecular Biology|August 15, 2006
Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1Jon C D Houtman, Hiroshi Yamaguchi, Mira Barda-Saad, et al.
Plos One|June 30, 2015
miR-155 Controls Lymphoproliferation in LAT Mutant Mice by Restraining T-Cell Apoptosis via SHIP-1/mTOR and PAK1/FOXO3/BIM PathwaysAlexandre K Rouquette-Jazdanian, Robert L Kortum, Wenmei Li, et al.
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