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Bioorganic & Medicinal Chemistry Letters|April 29, 2014
Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitorsRichard M Pastor, Jason D Burch, Steven Magnuson, et al.Bioorganic & Medicinal Chemistry Letters|January 11, 2011
Naphthalene/quinoline amides and sulfonylureas as potent and selective antagonists of the EP4 receptorJason D Burch, Julie Farand, John Colucci, et al.Bioorganic & Medicinal Chemistry Letters|February 23, 2008
Structure-activity relationships and pharmacokinetic parameters of quinoline acylsulfonamides as potent and selective antagonists of the EP(4) receptorJason D Burch, Michel Belley, Réjean Fortin, et al.ACS Medicinal Chemistry Letters|December 18, 2024
Discovery of Potent and Orally Bioavailable Pyrimidine Amide cGAS Inhibitors via Structure-Guided HybridizationPatrick Cyr, Lee D Fader, Jason D Burch, et al.Journal of Medicinal Chemistry|June 12, 2014
Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitorsJason D Burch, Kevin Lau, John J Barker, et al.Journal of Medicinal Chemistry|April 7, 2015
Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in VivoJason D Burch, Kathy Barrett, Yuan Chen, et al.Communications Chemistry|March 23, 2025
Structural insight into the cGAS active site explains differences between therapeutically relevant speciesAlexander M Skeldon, Li Wang, Nicolas Sgarioto, et al.Bioorganic & Medicinal Chemistry Letters|December 3, 2014
Design, synthesis and structure-activity relationships of a novel class of sulfonylpyridine inhibitors of Interleukin-2 inducible T-cell kinase (ITK)Giancarlo Trani, John J Barker, Steven M Bromidge, et al.Journal of Medicinal Chemistry|January 18, 2014
Back pocket flexibility provides group II p21-activated kinase (PAK) selectivity for type I 1/2 kinase inhibitorsSteven T Staben, Jianwen A Feng, Karen Lyle, et al.Bioorganic & Medicinal Chemistry Letters|October 22, 2013
Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK)Colin H MacKinnon, Kevin Lau, Jason D Burch, et al.Pageof 3