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Journal of Fungi (Basel, Switzerland)|April 16, 2020
The Dynamic Influence of Olorofim (F901318) on the Cell Morphology and Organization of Living Cells of Aspergillus fumigatusSaskia du Pré, Mike Birch, Derek Law, et al.
Plos One|October 3, 2012
The Aspergillus fumigatus dihydroxyacid dehydratase Ilv3A/IlvC is required for full virulenceJason D Oliver, Sarah J Kaye, Danny Tuckwell, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|May 20, 2005
Gene ontology mapping as an unbiased method for identifying molecular pathways and processes affected by toxicant exposure: application to acute effects caused by the rodent non-genotoxic carcinogen diethylhexylphthalateRichard A Currie, Vincent Bombail, Jason D Oliver, et al.
Antimicrobial Agents and Chemotherapy|June 13, 2018
Effect of the Novel Antifungal Drug F901318 (Olorofim) on Growth and Viability of Aspergillus fumigatusSaskia du Pré, Nicola Beckmann, Mariana Cruz Almeida, et al.
Emerging Microbes & Infections|February 3, 2022
Resistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistanceJochem B Buil, Jason D Oliver, Derek Law, et al.
The Journal of Biological Chemistry|February 12, 2004
The primary substrate binding site in the b' domain of ERp57 is adapted for endoplasmic reticulum lectin associationSarah J Russell, Lloyd W Ruddock, Kirsi E H Salo, et al.
Mbio|July 20, 2017
A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for PathogenicityAnna Johns, Daniel H Scharf, Fabio Gsaller, et al.
Mbio|December 5, 2019
Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of ResistanceWilliam Hope, Neil R H Stone, Adam Johnson, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 30, 2016
F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenaseJason D Oliver, Graham E M Sibley, Nicola Beckmann, et al.
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