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ACS Medicinal Chemistry Letters|January 21, 2022
Discovery of Spiro-azaindoline Inhibitors of Hematopoietic Progenitor Kinase 1 (HPK1)Bryan K Chan, Eileen Seward, Michael Lainchbury, et al.Science Translational Medicine|December 18, 2012
Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutationsZejuan Sheng, Shuo Zhang, Daisy Bustos, et al.Journal of Medicinal Chemistry|February 5, 2019
Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple MyelomaXiaojing Wang, Wesley Blackaby, Vivienne Allen, et al.Journal of Medicinal Chemistry|December 21, 2013
Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitorsAnthony A Estrada, Bryan K Chan, Charles Baker-Glenn, et al.Journal of Medicinal Chemistry|September 19, 2012
Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitorsAnthony A Estrada, Xingrong Liu, Charles Baker-Glenn, et al.Nature|October 19, 2017
USP7 small-molecule inhibitors interfere with ubiquitin bindingLorna Kategaya, Paola Di Lello, Lionel Rougé, et al.Pageof 2