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Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|
December 26, 2025
Drug Development
Jonathan A Sugam, Seth Robey, Sokreine Suon, et al.
Neuropharmacology
|
July 4, 2012
The novel phosphodiesterase 10A inhibitor THPP-1 has antipsychotic-like effects in rat and improves cognition in rat and rhesus monkey
Sean M Smith, Jason M Uslaner, Christopher D Cox, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 15, 2018
Indole acids as a novel PDE2 inhibitor chemotype that demonstrate pro-cognitive activity in multiple species
Shawn J Stachel, Melissa S Egbertson, Jenny Wai, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 27, 2016
Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis
Mark E Layton, Alexander J Reif, Timothy J Hartingh, et al.
Neuropharmacology
|
July 15, 2009
Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure
Christopher J Winrow, Keith Q Tanis, Duane R Reiss, et al.
Frontiers in Neuroscience
|
January 9, 2014
Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators
Andres D Ramirez, Anthony L Gotter, Steven V Fox, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
February 26, 2020
Pharmacological Characterization of the Novel and Selective <i>α</i>7 Nicotinic Acetylcholine Receptor-Positive Allosteric Modulator BNC375
Xiaohai Wang, Christopher Daley, Vanita Gakhar, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 23, 2010
3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts
Edward J Brnardic, Mark E Fraley, Robert M Garbaccio, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI
Joseph E Pero, Michael A Rossi, Michael J Kelly, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
December 18, 2008
The behavioral and neurochemical effects of a novel D-amino acid oxidase inhibitor compound 8 [4H-thieno [3,2-b]pyrrole-5-carboxylic acid] and D-serine
Sean M Smith, Jason M Uslaner, Lihang Yao, et al.
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Search research articles
Search
Showing results (51-60 of 71) with videos related to
Sort By:
Page
of 8
Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|
December 26, 2025
Drug Development
Jonathan A Sugam, Seth Robey, Sokreine Suon, et al.
Neuropharmacology
|
July 4, 2012
The novel phosphodiesterase 10A inhibitor THPP-1 has antipsychotic-like effects in rat and improves cognition in rat and rhesus monkey
Sean M Smith, Jason M Uslaner, Christopher D Cox, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 15, 2018
Indole acids as a novel PDE2 inhibitor chemotype that demonstrate pro-cognitive activity in multiple species
Shawn J Stachel, Melissa S Egbertson, Jenny Wai, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 27, 2016
Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis
Mark E Layton, Alexander J Reif, Timothy J Hartingh, et al.
Neuropharmacology
|
July 15, 2009
Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure
Christopher J Winrow, Keith Q Tanis, Duane R Reiss, et al.
Frontiers in Neuroscience
|
January 9, 2014
Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators
Andres D Ramirez, Anthony L Gotter, Steven V Fox, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
February 26, 2020
Pharmacological Characterization of the Novel and Selective <i>α</i>7 Nicotinic Acetylcholine Receptor-Positive Allosteric Modulator BNC375
Xiaohai Wang, Christopher Daley, Vanita Gakhar, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 23, 2010
3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts
Edward J Brnardic, Mark E Fraley, Robert M Garbaccio, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI
Joseph E Pero, Michael A Rossi, Michael J Kelly, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
December 18, 2008
The behavioral and neurochemical effects of a novel D-amino acid oxidase inhibitor compound 8 [4H-thieno [3,2-b]pyrrole-5-carboxylic acid] and D-serine
Sean M Smith, Jason M Uslaner, Lihang Yao, et al.
Page
of 8