Showing results (21-30 of 39) with videos related to
Sort By:
Pageof 4
Proceedings of the National Academy of Sciences of the United States of America|February 20, 2014
Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchangeMichael C Burns, Qi Sun, R Nathan Daniels, et al.Analytical Biochemistry|February 15, 2018
High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signalingMichael C Burns, Jennifer E Howes, Qi Sun, et al.ACS Medicinal Chemistry Letters|August 14, 2024
Fragment-Based Screen of SARS-CoV-2 Papain-like Protease (PLpro)Ashley J Taylor, Kangsa Amporndanai, Tyson A Rietz, et al.Bioorganic & Medicinal Chemistry Letters|July 26, 2005
Synthesis of tripeptides as potent Yersinia protein tyrosine phosphatase inhibitorsKyeong Lee, Shanthaveerappa K Boovanahalli, Ky-Youb Nam, et al.ACS Medicinal Chemistry Letters|September 28, 2018
Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RASJason R Abbott, Pratiq A Patel, Jennifer E Howes, et al.Journal of Medicinal Chemistry|April 1, 2020
Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC Inhibitors Using Fragment-Based Methods and Structure-Based DesignSelena Chacón Simon, Feng Wang, Lance R Thomas, et al.Journal of Medicinal Chemistry|June 2, 2018
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS SignalingJason R Abbott, Timothy R Hodges, R Nathan Daniels, et al.Journal of Medicinal Chemistry|January 17, 2025
Discovery of Small Molecules that Bind to Son of Sevenless 2 (SOS2)Krzysztof M Zak, Alex G Waterson, Leonhard Geist, et al.Molecular Cell|March 31, 2015
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYCLance R Thomas, Qingguo Wang, Brian C Grieb, et al.Journal of Medicinal Chemistry|February 2, 2026
Discovery of Spiro[chromane-2,4'-piperidine] Derivatives as Irreversible Inhibitors of SARS-CoV-2 Papain-like ProteaseQiangqiang Wei, Ashley J Taylor, Nagaraju Miriyala, et al.Pageof 4