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ACS Chemical Biology|May 7, 2019
Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation ApplicationsCarl C Ward, Jordan I Kleinman, Scott M Brittain, et al.
Chembiochem : a European Journal of Chemical Biology|October 17, 2015
Gift from Nature: Cyclomarin A Kills Mycobacteria and Malaria Parasites by Distinct Modes of ActionNathalie Bürstner, Silvio Roggo, Nils Ostermann, et al.
ACS Chemical Biology|November 22, 2018
Previously Uncharacterized Vacuolar-type ATPase Binding Site Discovered from Structurally Similar Compounds with Distinct Mechanisms of ActionAndrew C Wang, Helen T Pham, Jennifer M Lipps, et al.
ACS Chemical Biology|September 13, 2021
Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8David Remillard, Nikolas A Savage, Alexia T Kedves, et al.
Nature Chemical Biology|June 19, 2019
Harnessing the anti-cancer natural product nimbolide for targeted protein degradationJessica N Spradlin, Xirui Hu, Carl C Ward, et al.
Cell Death & Disease|January 11, 2022
PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancerAmrita Salvi, Alexandria N Young, Andrew C Huntsman, et al.
Scientific Reports|February 17, 2017
Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cellsDavid Estoppey, Jeffrey W Hewett, Chantale T Guy, et al.
ACS Chemical Biology|April 2, 2024
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening ProfilesJason R Thomas, Claude Shelton, Jason Murphy, et al.
Nature Communications|January 4, 2024
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistanceMartin Schröder, Martin Renatus, Xiaoyou Liang, et al.
Nature Chemical Biology|June 2, 2015
SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA miceJames Palacino, Susanne E Swalley, Cheng Song, et al.
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