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Clinical Pharmacology in Drug Development|August 10, 2018
Phase 1 Single- and Multiple-Ascending-Dose Randomized Studies of the Safety, Pharmacokinetics, and Pharmacodynamics of AG-348, a First-in-Class Allosteric Activator of Pyruvate Kinase R, in Healthy VolunteersHua Yang, Elizabeth Merica, Yue Chen, et al.Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society|November 29, 2020
Lumacaftor/ivacaftor in people with cystic fibrosis with an A455E-CFTR mutationGitte Berkers, Renske van der Meer, Harry Heijerman, et al.The Lancet. Respiratory Medicine|December 23, 2021
Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trialSivagurunathan Sutharsan, Edward F McKone, Damian G Downey, et al.Pageof 2