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Bioorganic & Medicinal Chemistry Letters|September 29, 2014
Scaffold hopping towards potent and selective JAK3 inhibitors: discovery of novel C-5 substituted pyrrolopyrazinesJavier de Vicente, Remy Lemoine, Mark Bartlett, et al.Journal of Medicinal Chemistry|March 21, 2013
De novo fragment design: a medicinal chemistry approach to fragment-based lead generationFrancisco X Talamas, Gloria Ao-Ieong, Ken A Brameld, et al.Journal of Medicinal Chemistry|September 28, 2013
Discovery of a novel series of potent non-nucleoside inhibitors of hepatitis C virus NS5BRyan C Schoenfeld, David L Bourdet, Ken A Brameld, et al.Analytica Chimica Acta|January 20, 2025
CRISPR-associated Plasmonic Colorimeter Method (Ca-PCM): A real-time RGB detection system for gold nanoparticles-based nucleic acid biosensorsHernán Alarcón-Iniesta, Guillermo de Arana, María López-Valls, et al.Journal of Environmental Management|July 18, 2016
The PRECOS framework: Measuring the impacts of the global changes on soils, water, agriculture on territories to better anticipate the futureFabienne Trolard, Guilhem Bourrié, Antoine Baillieux, et al.Journal of Medicinal Chemistry|March 20, 2018
Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial ActivityColin K Skepper, Robert J Moreau, Brent A Appleton, et al.Journal of Medicinal Chemistry|March 3, 2018
Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative BacteriaRobert J Moreau, Colin K Skepper, Brent A Appleton, et al.Movement Disorders : Official Journal of the Movement Disorder Society|February 22, 2023
LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's DiseaseDanna Jennings, Sarah Huntwork-Rodriguez, Maurits F J M Vissers, et al.Journal of Medicinal Chemistry|March 21, 2024
Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative DiseasesRobert A Craig, Javier De Vicente, Anthony A Estrada, et al.Science Immunology|November 8, 2024
Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunctionShengxiang Sun, Miki Hodel, Xiang Wang, et al.Pageof 3