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Organic & Biomolecular Chemistry|August 18, 2005
A new reactivity pattern for vinyl bromides: cine-substitution via palladium catalysed C-N coupling/Michael addition reactionsMichael C Willis, Jay Chauhan, William G Whittingham
Bioorganic & Medicinal Chemistry Letters|March 11, 2023
Discovery and anti-tumor activity of 4-(benzylamino)-6-(3,5-dimethylisoxazol-4-yl)quinolin-2(1H)-one (CG13250), a potent, selective and orally bioavailable BET bromodomain inhibitorJay Chauhan, Makoto Yoshioka, Sarah Pogash, et al.
Investigational New Drugs|April 28, 2026
Prostate cancer cells' growth is decreased by novel MYC inhibitorsBita Nickkholgh, Joseph McGrath, Sivanandane Sittadjody, et al.
Bioorganic & Medicinal Chemistry Letters|May 26, 2019
Optimization of a small-molecule Lipid II binderJay Chauhan, Steven M Kwasny, Steven Fletcher, et al.
RSC Medicinal Chemistry|February 10, 2023
Discovery of N-sulfonylated aminosalicylic acids as dual MCL-1/BCL-xL inhibitorsLijia Chen, Jay Chauhan, Jeremy L Yap, et al.
Organic Letters|September 23, 2010
Phosphonoxins III: synthesis of α-aminophosphonate analogs of antifungal polyoxins with anti-Giardia activityMichael Staake, Jay Chauhan, Ding Zhou, et al.
RSC Medicinal Chemistry|April 27, 2026
Lead optimization of 5jc21 (CG13250), a quinolin-2(1H)-one-based inhibitor of the BRD4 member of the bromodomain and extraterminal (BET) family of proteinsJay Chauhan, Sarah Pogash, Makoto Yoshioka, et al.
Chemmedchem|July 1, 2014
Discovery of methyl 4'-methyl-5-(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)-[1,1'-biphenyl]-3-carboxylate, an improved small-molecule inhibitor of c-Myc-max dimerizationJay Chauhan, Huabo Wang, Jeremy L Yap, et al.
Drug Design, Development and Therapy|February 28, 2020
Optimization of a Benzothiazole Indolene Scaffold Targeting Bacterial Cell Wall AssemblyJay Chauhan, Wenbo Yu, Steven Cardinale, et al.
Biochemical and Biophysical Research Communications|January 25, 2017
CG13250, a novel bromodomain inhibitor, suppresses proliferation of multiple myeloma cells in an orthotopic mouse modelNatsuki Imayoshi, Makoto Yoshioka, Jay Chauhan, et al.
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