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Jay P McLaughlin

Showing results (81-90 of 109) with videos related to

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The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|May 14, 2004
Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor toleranceMei Xu, Michael Petraschka, Jay P McLaughlin, et al.
Organic & Biomolecular Chemistry|September 7, 2017
A one-pot multicomponent approach to a new series of morphine derivatives and their biological evaluationJiaan Shao, Richard A Houghten, Colette T Dooley, et al.
Chemmedchem|July 16, 2011
Unexpected opioid activity profiles of analogues of the novel peptide kappa opioid receptor ligand CJ-15,208Jane V Aldrich, Santosh S Kulkarni, Sanjeewa N Senadheera, et al.
Proteomics|January 26, 2022
Novel histone modifications in microglia derived from a mouse model of chronic painPing Zhang, Jennifer Guergues, Amy R Alleyne, et al.
ACS Combinatorial Science|December 15, 2015
Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734,821 Pyrrolidine Bis-piperazinesRichard A Houghten, Michelle L Ganno, Jay P McLaughlin, et al.
The AAPS Journal|July 22, 2020
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In VivoSebastiano Intagliata, Abhisheak Sharma, Tamara I King, et al.
British Journal of Pharmacology|June 21, 2020
Multifunctional opioid receptor agonism and antagonism by a novel macrocyclic tetrapeptide prevents reinstatement of morphine-seeking behaviourAriana C Brice-Tutt, Lisa L Wilson, Shainnel O Eans, et al.
ACS Chemical Neuroscience|April 7, 2020
Design, Synthesis, and Characterization of the Macrocyclic Tetrapeptide <i>cyclo</i>[Pro-Sar-Phe-d-Phe]: A Mixed Opioid Receptor Agonist-Antagonist Following Oral AdministrationMichael J Ferracane, Ariana C Brice-Tutt, Jeremy S Coleman, et al.
ACS Medicinal Chemistry Letters|March 19, 2025
Peripherally Restricted Fused Heterocyclic Peptidomimetic Multifunctional Opioid Agonists as Novel, Potent AnalgesicsHaylee R Hammond, Prakash Chaudhari, Ashley Bunnell, et al.
Pain|July 6, 2026
Peripheral kappa opioid receptors modulate cold hypersensitivity in a mouse model of chemotherapy-induced neuropathyManish K Madasu, Loc V Thang, Christian C Ohazurume, et al.
Pageof 11

Showing results (81-90 of 109) with videos related to

Sort By:
Pageof 11
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|May 14, 2004
Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor toleranceMei Xu, Michael Petraschka, Jay P McLaughlin, et al.
Organic & Biomolecular Chemistry|September 7, 2017
A one-pot multicomponent approach to a new series of morphine derivatives and their biological evaluationJiaan Shao, Richard A Houghten, Colette T Dooley, et al.
Chemmedchem|July 16, 2011
Unexpected opioid activity profiles of analogues of the novel peptide kappa opioid receptor ligand CJ-15,208Jane V Aldrich, Santosh S Kulkarni, Sanjeewa N Senadheera, et al.
Proteomics|January 26, 2022
Novel histone modifications in microglia derived from a mouse model of chronic painPing Zhang, Jennifer Guergues, Amy R Alleyne, et al.
ACS Combinatorial Science|December 15, 2015
Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734,821 Pyrrolidine Bis-piperazinesRichard A Houghten, Michelle L Ganno, Jay P McLaughlin, et al.
The AAPS Journal|July 22, 2020
Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In VivoSebastiano Intagliata, Abhisheak Sharma, Tamara I King, et al.
British Journal of Pharmacology|June 21, 2020
Multifunctional opioid receptor agonism and antagonism by a novel macrocyclic tetrapeptide prevents reinstatement of morphine-seeking behaviourAriana C Brice-Tutt, Lisa L Wilson, Shainnel O Eans, et al.
ACS Chemical Neuroscience|April 7, 2020
Design, Synthesis, and Characterization of the Macrocyclic Tetrapeptide <i>cyclo</i>[Pro-Sar-Phe-d-Phe]: A Mixed Opioid Receptor Agonist-Antagonist Following Oral AdministrationMichael J Ferracane, Ariana C Brice-Tutt, Jeremy S Coleman, et al.
ACS Medicinal Chemistry Letters|March 19, 2025
Peripherally Restricted Fused Heterocyclic Peptidomimetic Multifunctional Opioid Agonists as Novel, Potent AnalgesicsHaylee R Hammond, Prakash Chaudhari, Ashley Bunnell, et al.
Pain|July 6, 2026
Peripheral kappa opioid receptors modulate cold hypersensitivity in a mouse model of chemotherapy-induced neuropathyManish K Madasu, Loc V Thang, Christian C Ohazurume, et al.
Pageof 11