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JACC. Advances|June 28, 2024
Homozygous Familial Hypercholesterolemia in Canada: An Observational StudyLeslie Brown, Isabelle Ruel, Alexis Baass, et al.The Lancet. Diabetes & Endocrinology|December 21, 2025
Zodasiran, an RNAi therapeutic targeting ANGPTL3, for treating patients with homozygous familial hypercholesterolaemia (GATEWAY): an open-label, randomised, phase 2 trialFrederick J Raal, Jean Bergeron, Daniel Gaudet, et al.The New England Journal of Medicine|September 1, 2020
Evolocumab in Pediatric Heterozygous Familial HypercholesterolemiaRaul D Santos, Andrea Ruzza, G Kees Hovingh, et al.The Lancet. Diabetes & Endocrinology|September 8, 2022
Paediatric patients with heterozygous familial hypercholesterolaemia treated with evolocumab for 80 weeks (HAUSER-OLE): a single-arm, multicentre, open-label extension of HAUSER-RCTRaul D Santos, Andrea Ruzza, G Kees Hovingh, et al.Nature Medicine|March 6, 2023
Evinacumab in severe hypertriglyceridemia with or without lipoprotein lipase pathway mutations: a phase 2 randomized trialRobert S Rosenson, Daniel Gaudet, Christie M Ballantyne, et al.Circulation. Cardiovascular Genetics|September 13, 2014
CKM and LILRB5 are associated with serum levels of creatine kinaseMarie-Pierre Dubé, Rosa Zetler, Amina Barhdadi, et al.Journal of Clinical Lipidology|January 28, 2024
Sex differences in the presentation, treatment and outcomes of patients with homozygous familial hypercholesterolemiaZobaida Al-Baldawi, Leslie Brown, Isabelle Ruel, et al.Clinical Chemistry|October 18, 2017
Imputation of Baseline LDL Cholesterol Concentration in Patients with Familial Hypercholesterolemia on Statins or EzetimibeIsabelle Ruel, Sumayah Aljenedil, Iman Sadri, et al.The New England Journal of Medicine|August 8, 2019
Volanesorsen and Triglyceride Levels in Familial Chylomicronemia SyndromeJoseph L Witztum, Daniel Gaudet, Steven D Freedman, et al.Journal of Clinical Lipidology|December 5, 2024
Extreme LDL-C concentration is associated with increased cardiovascular disease in women with homozygous familial hypercholesterolemiaMartine Paquette, Isabelle Ruel, Simon-Pierre Guay, et al.Pageof 18