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Blood|October 22, 2008
Phase I study of obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemiaSusan M O'Brien, David F Claxton, Michael Crump, et al.
Plos One|July 23, 2013
Anti-metastatic and anti-tumor growth effects of Origanum majorana on highly metastatic human breast cancer cells: inhibition of NFκB signaling and reduction of nitric oxide productionYusra Al Dhaheri, Samir Attoub, Kholoud Arafat, et al.
Autophagy|August 24, 2010
The combination of a histone deacetylase inhibitor with the BH3-mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagyYue Wei, Tapan Kadia, Weigang Tong, et al.
Cancer Research|May 3, 2008
Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax)Marina Konopleva, Julie Watt, Rooha Contractor, et al.
Cancer Research|October 1, 2013
Genetic and pharmacologic inhibition of mTORC1 promotes EMT by a TGF-β-independent mechanismIvan Mikaelian, Mouhannad Malek, Rudy Gadet, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|June 12, 2010
The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagyYue Wei, Tapan Kadia, Weigang Tong, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|June 12, 2010
Phase I dose finding studies of obatoclax (GX15-070), a small molecule pan-BCL-2 family antagonist, in patients with advanced solid tumors or lymphomaJimmy J Hwang, John Kuruvilla, David Mendelson, et al.
Cancers|September 14, 2024
Sulfamoylated Estradiol Analogs Targeting the Actin and Microtubule Cytoskeletons Demonstrate Anti-Cancer Properties In Vitro and In OvoAnne Elisabeth Mercier, Anna Margaretha Joubert, Renaud Prudent, et al.
Scientific Reports|February 19, 2016
Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathwaysHussain El Hasasna, Alaaeldin Saleh, Halima Al Samri, et al.
Molecular Pharmacology|January 3, 2006
Use of penetrating peptides interacting with PP1/PP2A proteins as a general approach for a drug phosphatase technologyJulien Guergnon, Frédéric Dessauge, Victoria Dominguez, et al.
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