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Frontiers in Molecular Neuroscience|January 10, 2018
PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2Laura Civiero, Susanna Cogo, Anneleen Kiekens, et al.
Molecular Systems Biology|January 29, 2026
Multi-cohort, cross-species urinary proteomics reveals signatures of LRRK2 dysfunction in Parkinson's diseaseDuc Tung Vu, William Sibran, Andreas Metousis, et al.
Brain Research|January 12, 2022
The Roc domain of LRRK2 as a hub for protein-protein interactions: a focus on PAK6 and its impact on RAB phosphorylationSusanna Cogo, Franz Y Ho, Elena Tosoni, et al.
Frontiers in Molecular Neuroscience|January 3, 2024
PAK6-mediated phosphorylation of PPP2R2C regulates LRRK2-PP2A complex formationLucia Iannotta, Marco Emanuele, Giulia Favetta, et al.
Journal of Neurochemistry|September 17, 2015
Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brainLaura Civiero, Maria Daniela Cirnaru, Alexandra Beilina, et al.
Cell Death & Disease|October 17, 2024
PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific mannerLucia Iannotta, Rachel Fasiczka, Giulia Favetta, et al.
The Journal of Biological Chemistry|November 27, 2013
A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylationBernard M H Law, Victoria A Spain, Veronica H L Leinster, et al.
Cells|March 25, 2022
A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, RespectivelyAntoine Marchand, Alessia Sarchione, Panagiotis S Athanasopoulos, et al.
The Biochemical Journal|May 14, 2026
Regulation between LRRK2 and PP2A signaling in cellular models of Parkinsons diseasePanagiotis S Athanasopoulos, Anna Memou, Franz Y Ho, et al.
Chemical Science|January 29, 2025
Functionally active modulators targeting the LRRK2 WD40 repeat domain identified by FRASE-bot in CACHE Challenge #1Akhila Mettu, Marta Glavatskikh, Xiaowen Wang, et al.
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