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The Journal of Organic Chemistry|February 14, 2006
Heck, direct arylation, and hydrogenation: two or three sequential reactions from a single catalystJean-Philippe Leclerc, Mathieu André, Keith FagnouBioorganic & Medicinal Chemistry Letters|November 22, 2011
Discovery of potent and liver-selective stearoyl-CoA desaturase (SCD) inhibitors in an acyclic linker seriesNicolas Lachance, Sébastien Guiral, Zheng Huang, et al.Journal of the American Chemical Society|February 14, 2009
Palladium-catalyzed direct arylation of azine and azole N-oxides: reaction development, scope and applications in synthesisLouis-Charles Campeau, David R Stuart, Jean-Philippe Leclerc, et al.Bioorganic & Medicinal Chemistry Letters|September 20, 2011
Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitorsJean-Philippe Leclerc, Jean-Pierre Falgueyret, Mélina Girardin, et al.Bioorganic & Medicinal Chemistry Letters|August 30, 2011
Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: from systemic to liver-targeting inhibitorsYeeman K Ramtohul, David Powell, Jean-Philippe Leclerc, et al.Bioorganic & Medicinal Chemistry Letters|January 3, 2012
Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine seriesNicolas Lachance, Yves Gareau, Sébastien Guiral, et al.ACS Medicinal Chemistry Letters|December 18, 2020
Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory ActivityRamsay E Beveridge, Heidi Ackerly Wallweber, Avi Ashkenazi, et al.Journal of Medicinal Chemistry|May 15, 2024
Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma ModelMarie-Gabrielle Braun, Avi Ashkenazi, Ramsay E Beveridge, et al.ACS Medicinal Chemistry Letters|September 22, 2023
Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2)Mingshuo Zeng, Jessica M Grandner, Marian C Bryan, et al.ACS Medicinal Chemistry Letters|June 17, 2026
Optimization and In Vivo Characterization of a Series of Cbl‑b Inactive-State InhibitorsMichael J Lambrecht, Jun Liang, Peter Man-Un Ung, et al.Pageof 2