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Analytical Biochemistry|March 5, 2009
Development of a homogeneous immunoassay for the detection of angiotensin I in plasma using AlphaLISA acceptor beads technologyElizabeth Cauchon, Susana Liu, M David Percival, et al.Bioorganic & Medicinal Chemistry Letters|June 5, 2007
Primary amides as selective inhibitors of cathepsin KSerge Léger, Christopher I Bayly, W Cameron Black, et al.Bioorganic & Medicinal Chemistry Letters|July 21, 2004
Rational design of potent and selective NH-linked aryl/heteroaryl cathepsin K inhibitorsJoël Robichaud, Christopher Bayly, Renata Oballa, et al.Nature Communications|February 12, 2014
Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiaeElena Fossati, Andrew Ekins, Lauren Narcross, et al.The Journal of Biological Chemistry|July 9, 2011
Impact of primer-induced conformational dynamics of HIV-1 reverse transcriptase on polymerase translocation and inhibitionAnick Auger, Greg L Beilhartz, Siqi Zhu, et al.Bioorganic & Medicinal Chemistry Letters|October 12, 2010
2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitorsDavid A Powell, Yeeman Ramtohul, Marie-Eve Lebrun, et al.Journal of Medicinal Chemistry|November 24, 2005
Lysosomotropism of basic cathepsin K inhibitors contributes to increased cellular potencies against off-target cathepsins and reduced functional selectivityJean-Pierre Falgueyret, Sylvie Desmarais, Renata Oballa, et al.Analytical Biochemistry|November 24, 2004
An activity-based probe for the determination of cysteine cathepsin protease activities in whole cellsJean-Pierre Falgueyret, W Cameron Black, Wanda Cromlish, et al.Bioorganic & Medicinal Chemistry Letters|September 20, 2011
Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitorsJean-Philippe Leclerc, Jean-Pierre Falgueyret, Mélina Girardin, et al.Bioorganic & Medicinal Chemistry Letters|December 17, 2009
Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438)Serge Léger, W Cameron Black, Denis Deschenes, et al.Pageof 5