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Bioorganic & Medicinal Chemistry Letters|March 28, 2012
Design and synthesis of potent, isoxazole-containing renin inhibitorsPierre-André Fournier, Mélissa Arbour, Elizabeth Cauchon, et al.Journal of Medicinal Chemistry|September 25, 2008
Identification of a nonbasic, nitrile-containing cathepsin K inhibitor (MK-1256) that is efficacious in a monkey model of osteoporosisJöel Robichaud, W Cameron Black, Michel Thérien, et al.Bioorganic & Medicinal Chemistry Letters|January 18, 2006
Identification of a potent and selective non-basic cathepsin K inhibitorChun Sing Li, Denis Deschenes, Sylvie Desmarais, et al.Bioorganic & Medicinal Chemistry Letters|January 15, 2011
Difluoroethylamines as an amide isostere in inhibitors of cathepsin KElise Isabel, Christophe Mellon, Michael J Boyd, et al.Bioorganic & Medicinal Chemistry Letters|June 7, 2011
Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of tertiary alcohol-bearing piperidinesAustin Chen, Elizabeth Cauchon, Amandine Chefson, et al.Bioorganic & Medicinal Chemistry Letters|May 31, 2011
Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of pyridone-substituted piperidinesAustin Chen, Louis-Charles Campeau, Elizabeth Cauchon, et al.Bioorganic & Medicinal Chemistry Letters|January 30, 2008
The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin KJacques Yves Gauthier, Nathalie Chauret, Wanda Cromlish, et al.Bioorganic & Medicinal Chemistry Letters|January 12, 2010
The discovery of MK-0674, an orally bioavailable cathepsin K inhibitorElise Isabel, Kevin P Bateman, Nathalie Chauret, et al.Bioorganic & Medicinal Chemistry Letters|January 14, 2014
Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV virusesBernard Côté, Jason D Burch, Ernest Asante-Appiah, et al.Journal of Medicinal Chemistry|November 24, 2005
Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin KJames T Palmer, Clifford Bryant, Dan-Xiong Wang, et al.Pageof 5