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Frontiers in Oncology|August 23, 2018
The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and NeoplasiaJeffrey A Rappaport, Scott A Waldman
Expert Review of Clinical Pharmacology|September 18, 2020
An update on guanylyl cyclase C in the diagnosis, chemoprevention, and treatment of colorectal cancerJeffrey A Rappaport, Scott A Waldman
Oncotarget|December 22, 2017
GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stressCrystal L Kraft, Jeffrey A Rappaport, Adam E Snook, et al.
Biomarkers in Medicine|January 20, 2021
Guanylyl cyclase C as a biomarker for immunotherapies for the treatment of gastrointestinal malignanciesJohn C Flickinger, Jeffrey A Rappaport, Joshua R Barton, et al.
Cancer Biology & Therapy|February 11, 2020
APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axisErik S Blomain, Jeffrey A Rappaport, Amanda M Pattison, et al.
The Journal of Pharmacology and Experimental Therapeutics|May 19, 2019
δ-Tocopherol Effect on Endocytosis and Its Combination with Enzyme Replacement Therapy for Lysosomal Disorders: A New Type of Drug Interaction?Rachel L Manthe, Jeffrey A Rappaport, Yan Long, et al.
Human Pathology|February 5, 2019
Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasiaBabar Bashir, Dante J Merlino, Jeffrey A Rappaport, et al.
NPJ Vaccines|June 23, 2022
Chimeric adenoviral (Ad5.F35) and listeria vector prime-boost immunization is safe and effective for cancer immunotherapyJohn C Flickinger, Ross E Staudt, Jagmohan Singh, et al.
Journal for Immunotherapy of Cancer|August 22, 2020
Chimeric Ad5.F35 vector evades anti-adenovirus serotype 5 neutralization opposing GUCY2C-targeted antitumor immunityJohn C Flickinger, Jagmohan Singh, Robert Carlson, et al.
Cellular and Molecular Gastroenterology and Hepatology|December 26, 2021
A β-Catenin-TCF-Sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal CancerJeffrey A Rappaport, Ariana A Entezari, Adi Caspi, et al.
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