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Jeffrey D Rothstein

Showing results (191-200 of 215) with videos related to

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Science Translational Medicine|October 27, 2021
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G<sub>4</sub>C<sub>2</sub>) repeat expansion in vitro and in vivo ALS modelsJessica A Bush, Haruo Aikawa, Rita Fuerst, et al.
Plos One|May 21, 2014
Safety, pharmacokinetic, and functional effects of the nogo-a monoclonal antibody in amyotrophic lateral sclerosis: a randomized, first-in-human clinical trialVincent Meininger, Pierre-François Pradat, Andrea Corse, et al.
The Lancet. Neurology|July 26, 2024
Safety, tolerability, and pharmacokinetics of antisense oligonucleotide BIIB078 in adults with C9orf72-associated amyotrophic lateral sclerosis: a phase 1, randomised, double blinded, placebo-controlled, multiple ascending dose studyLeonard H van den Berg, Jeffrey D Rothstein, Pamela J Shaw, et al.
Science Translational Medicine|September 14, 2022
Poly(ADP-ribose) promotes toxicity of <i>C9ORF72</i> arginine-rich dipeptide repeat proteinsJunli Gao, Quinlan T Mewborne, Amandeep Girdhar, et al.
Neuron|August 19, 2014
Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALSZhaoming Su, Yongjie Zhang, Tania F Gendron, et al.
Medrxiv : the Preprint Server for Health Sciences|February 6, 2026
Is <i>SORL1</i> a common genetic target across neurodegenerative diseases?: A multi-ancestry biobank scale assessmentMarzieh Khani, Sheila N Yeboah, Catalina Cerquera-Cleves, et al.
Neuron|September 13, 2017
Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALSZhaoming Su, Yongjie Zhang, Tania F Gendron, et al.
Brain : a Journal of Neurology|May 26, 2026
Is SORL1 a common genetic target across neurodegenerative diseases? A multi-ancestry biobank studyMarzieh Khani, Sheila N Yeboah, Catalina Cerquera-Cleves, et al.
Neuron|January 18, 2019
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's DiseaseBahareh Eftekharzadeh, J Gavin Daigle, Larisa E Kapinos, et al.
Neuron|September 7, 2018
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's DiseaseBahareh Eftekharzadeh, J Gavin Daigle, Larisa E Kapinos, et al.
Pageof 22

Showing results (191-200 of 215) with videos related to

Sort By:
Pageof 22
Science Translational Medicine|October 27, 2021
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G<sub>4</sub>C<sub>2</sub>) repeat expansion in vitro and in vivo ALS modelsJessica A Bush, Haruo Aikawa, Rita Fuerst, et al.
Plos One|May 21, 2014
Safety, pharmacokinetic, and functional effects of the nogo-a monoclonal antibody in amyotrophic lateral sclerosis: a randomized, first-in-human clinical trialVincent Meininger, Pierre-François Pradat, Andrea Corse, et al.
The Lancet. Neurology|July 26, 2024
Safety, tolerability, and pharmacokinetics of antisense oligonucleotide BIIB078 in adults with C9orf72-associated amyotrophic lateral sclerosis: a phase 1, randomised, double blinded, placebo-controlled, multiple ascending dose studyLeonard H van den Berg, Jeffrey D Rothstein, Pamela J Shaw, et al.
Science Translational Medicine|September 14, 2022
Poly(ADP-ribose) promotes toxicity of <i>C9ORF72</i> arginine-rich dipeptide repeat proteinsJunli Gao, Quinlan T Mewborne, Amandeep Girdhar, et al.
Neuron|August 19, 2014
Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALSZhaoming Su, Yongjie Zhang, Tania F Gendron, et al.
Medrxiv : the Preprint Server for Health Sciences|February 6, 2026
Is <i>SORL1</i> a common genetic target across neurodegenerative diseases?: A multi-ancestry biobank scale assessmentMarzieh Khani, Sheila N Yeboah, Catalina Cerquera-Cleves, et al.
Neuron|September 13, 2017
Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALSZhaoming Su, Yongjie Zhang, Tania F Gendron, et al.
Brain : a Journal of Neurology|May 26, 2026
Is SORL1 a common genetic target across neurodegenerative diseases? A multi-ancestry biobank studyMarzieh Khani, Sheila N Yeboah, Catalina Cerquera-Cleves, et al.
Neuron|January 18, 2019
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's DiseaseBahareh Eftekharzadeh, J Gavin Daigle, Larisa E Kapinos, et al.
Neuron|September 7, 2018
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's DiseaseBahareh Eftekharzadeh, J Gavin Daigle, Larisa E Kapinos, et al.
Pageof 22