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Nature Communications|April 20, 2022
Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitorsKristin M Zimmerman Savill, Brian B Lee, Jason Oeh, et al.Neuron|June 23, 2017
Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in NeuronsDerek S Welsbie, Katherine L Mitchell, Vinod Jaskula-Ranga, et al.Science Signaling|August 4, 2021
A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activationOrna Ernst, Jing Sun, Bin Lin, et al.Oncotarget|October 27, 2015
Aurora B kinase is a potent and selective target in MYCN-driven neuroblastomaDominik Bogen, Jun S Wei, David O Azorsa, et al.Cell|July 30, 2019
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its MobilityJane Guan, Wei Zhou, Marc Hafner, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|February 7, 2019
Integrated Genomic and Functional microRNA Analysis Identifies miR-30-5p as a Tumor Suppressor and Potential Therapeutic Nanomedicine in Head and Neck CancerAnthony D Saleh, Hui Cheng, Scott E Martin, et al.Proceedings of the National Academy of Sciences of the United States of America|January 29, 2014
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cellsLesley A Mathews Griner, Rajarshi Guha, Paul Shinn, et al.Proceedings of the National Academy of Sciences of the United States of America|February 23, 2013
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell deathDerek S Welsbie, Zhiyong Yang, Yan Ge, et al.Nature|May 6, 2021
ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanomaIvana Yen, Frances Shanahan, Jeeyun Lee, et al.Nature|October 19, 2017
USP7 small-molecule inhibitors interfere with ubiquitin bindingLorna Kategaya, Paola Di Lello, Lionel Rougé, et al.Pageof 9