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Jennafer Dotson

Showing results (1-10 of 11) with videos related to

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Journal of Chemical Information and Modeling|November 15, 2011
DEGAS: sharing and tracking target compound ideas with external collaboratorsMan-Ling Lee, Ignacio Aliagas, Jennafer Dotson, et al.
Journal of Medicinal Chemistry|May 1, 2009
A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora BIgnacio Aliagas-Martin, Dan Burdick, Laura Corson, et al.
Journal of Medicinal Chemistry|October 12, 2011
Rational design of phosphoinositide 3-kinase α inhibitors that exhibit selectivity over the phosphoinositide 3-kinase β isoformTimothy P Heffron, Binqing Wei, Alan Olivero, et al.
Journal of Medicinal Chemistry|September 6, 2012
The design and identification of brain penetrant inhibitors of phosphoinositide 3-kinase αTimothy P Heffron, Laurent Salphati, Bruno Alicke, et al.
Bioorganic & Medicinal Chemistry Letters|March 30, 2010
Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitorTimothy P Heffron, Megan Berry, Georgette Castanedo, et al.
ACS Medicinal Chemistry Letters|January 29, 2016
Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFRMarian C Bryan, Daniel J Burdick, Bryan K Chan, et al.
Journal of Medicinal Chemistry|November 11, 2014
Discovery of selective and noncovalent diaminopyrimidine-based inhibitors of epidermal growth factor receptor containing the T790M resistance mutationEmily J Hanan, Charles Eigenbrot, Marian C Bryan, et al.
Journal of Medicinal Chemistry|May 14, 2013
Discovery of 2-{3-[2-(1-isopropyl-3-methyl-1H-1,2-4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide (GDC-0032): a β-sparing phosphoinositide 3-kinase inhibitor with high unbound exposure and robust in vivo antitumor activityChudi O Ndubaku, Timothy P Heffron, Steven T Staben, et al.
Journal of Medicinal Chemistry|August 27, 2016
Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor InhibitorBryan K Chan, Emily J Hanan, Krista K Bowman, et al.
Journal of Medicinal Chemistry|December 21, 2013
Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitorsAnthony A Estrada, Bryan K Chan, Charles Baker-Glenn, et al.
Pageof 2

Showing results (1-10 of 11) with videos related to

Sort By:
Pageof 2
Journal of Chemical Information and Modeling|November 15, 2011
DEGAS: sharing and tracking target compound ideas with external collaboratorsMan-Ling Lee, Ignacio Aliagas, Jennafer Dotson, et al.
Journal of Medicinal Chemistry|May 1, 2009
A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora BIgnacio Aliagas-Martin, Dan Burdick, Laura Corson, et al.
Journal of Medicinal Chemistry|October 12, 2011
Rational design of phosphoinositide 3-kinase α inhibitors that exhibit selectivity over the phosphoinositide 3-kinase β isoformTimothy P Heffron, Binqing Wei, Alan Olivero, et al.
Journal of Medicinal Chemistry|September 6, 2012
The design and identification of brain penetrant inhibitors of phosphoinositide 3-kinase αTimothy P Heffron, Laurent Salphati, Bruno Alicke, et al.
Bioorganic & Medicinal Chemistry Letters|March 30, 2010
Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitorTimothy P Heffron, Megan Berry, Georgette Castanedo, et al.
ACS Medicinal Chemistry Letters|January 29, 2016
Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFRMarian C Bryan, Daniel J Burdick, Bryan K Chan, et al.
Journal of Medicinal Chemistry|November 11, 2014
Discovery of selective and noncovalent diaminopyrimidine-based inhibitors of epidermal growth factor receptor containing the T790M resistance mutationEmily J Hanan, Charles Eigenbrot, Marian C Bryan, et al.
Journal of Medicinal Chemistry|May 14, 2013
Discovery of 2-{3-[2-(1-isopropyl-3-methyl-1H-1,2-4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide (GDC-0032): a β-sparing phosphoinositide 3-kinase inhibitor with high unbound exposure and robust in vivo antitumor activityChudi O Ndubaku, Timothy P Heffron, Steven T Staben, et al.
Journal of Medicinal Chemistry|August 27, 2016
Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor InhibitorBryan K Chan, Emily J Hanan, Krista K Bowman, et al.
Journal of Medicinal Chemistry|December 21, 2013
Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitorsAnthony A Estrada, Bryan K Chan, Charles Baker-Glenn, et al.
Pageof 2