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Jennifer R Allen

Showing results (11-20 of 35) with videos related to

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ACS Medicinal Chemistry Letters|July 21, 2016
Discovery of Phosphodiesterase 10A (PDE10A) PET Tracer AMG 580 to Support Clinical StudiesEssa Hu, Ning Chen, Roxanne K Kunz, et al.
Bioorganic & Medicinal Chemistry Letters|August 30, 2008
Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1alpha prolyl hydroxylase-2 inhibitorsMike Frohn, Vellarkad Viswanadhan, Alexander J Pickrell, et al.
ACS Medicinal Chemistry Letters|January 16, 2015
Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell ViabilityPaul E Harrington, Kaustav Biswas, David Malwitz, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|September 28, 2004
Vaccination of patients with small-cell lung cancer with synthetic fucosyl GM-1 conjugated to keyhole limpet hemocyaninLee M Krug, Govind Ragupathi, Chandra Hood, et al.
Bioorganic & Medicinal Chemistry Letters|June 13, 2020
The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacementMichael Frohn, Longbin Liu, Aaron C Siegmund, et al.
Bioorganic & Medicinal Chemistry Letters|November 15, 2012
Discovery of selective biaryl ethers as PDE10A inhibitors: improvement in potency and mitigation of Pgp-mediated effluxRobert M Rzasa, Essa Hu, Shannon Rumfelt, et al.
ACS Medicinal Chemistry Letters|June 20, 2014
Discovery of Novel Imidazo[4,5-b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A)Essa Hu, Kristin Andrews, Samer Chmait, et al.
Journal of Medicinal Chemistry|October 10, 2013
Design, optimization, and biological evaluation of novel keto-benzimidazoles as potent and selective inhibitors of phosphodiesterase 10A (PDE10A)Essa Hu, Roxanne K Kunz, Ning Chen, et al.
Journal of Medicinal Chemistry|October 8, 2019
Discovery of AM-6494: A Potent and Orally Efficacious β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2Liping H Pettus, Matthew P Bourbeau, Jodi Bradley, et al.
Bioorganic & Medicinal Chemistry Letters|June 27, 2008
Discovery of novel hydroxy-thiazoles as HIF-alpha prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluationChristopher M Tegley, Vellarkad N Viswanadhan, Kaustav Biswas, et al.
Pageof 4

Showing results (11-20 of 35) with videos related to

Sort By:
Pageof 4
ACS Medicinal Chemistry Letters|July 21, 2016
Discovery of Phosphodiesterase 10A (PDE10A) PET Tracer AMG 580 to Support Clinical StudiesEssa Hu, Ning Chen, Roxanne K Kunz, et al.
Bioorganic & Medicinal Chemistry Letters|August 30, 2008
Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1alpha prolyl hydroxylase-2 inhibitorsMike Frohn, Vellarkad Viswanadhan, Alexander J Pickrell, et al.
ACS Medicinal Chemistry Letters|January 16, 2015
Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell ViabilityPaul E Harrington, Kaustav Biswas, David Malwitz, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|September 28, 2004
Vaccination of patients with small-cell lung cancer with synthetic fucosyl GM-1 conjugated to keyhole limpet hemocyaninLee M Krug, Govind Ragupathi, Chandra Hood, et al.
Bioorganic & Medicinal Chemistry Letters|June 13, 2020
The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacementMichael Frohn, Longbin Liu, Aaron C Siegmund, et al.
Bioorganic & Medicinal Chemistry Letters|November 15, 2012
Discovery of selective biaryl ethers as PDE10A inhibitors: improvement in potency and mitigation of Pgp-mediated effluxRobert M Rzasa, Essa Hu, Shannon Rumfelt, et al.
ACS Medicinal Chemistry Letters|June 20, 2014
Discovery of Novel Imidazo[4,5-b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A)Essa Hu, Kristin Andrews, Samer Chmait, et al.
Journal of Medicinal Chemistry|October 10, 2013
Design, optimization, and biological evaluation of novel keto-benzimidazoles as potent and selective inhibitors of phosphodiesterase 10A (PDE10A)Essa Hu, Roxanne K Kunz, Ning Chen, et al.
Journal of Medicinal Chemistry|October 8, 2019
Discovery of AM-6494: A Potent and Orally Efficacious β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2Liping H Pettus, Matthew P Bourbeau, Jodi Bradley, et al.
Bioorganic & Medicinal Chemistry Letters|June 27, 2008
Discovery of novel hydroxy-thiazoles as HIF-alpha prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluationChristopher M Tegley, Vellarkad N Viswanadhan, Kaustav Biswas, et al.
Pageof 4