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Cancer Research|July 5, 2023
Acquired Secondary HER2 Mutations Enhance HER2/MAPK Signaling and Promote Resistance to HER2 Kinase Inhibition in Breast CancerArnaldo Marín, Abdullah Al Mamun, Hima Patel, et al.Elife|May 5, 2022
Heterogeneity of the GFP fitness landscape and data-driven protein designLouisa Gonzalez Somermeyer, Aubin Fleiss, Alexander S Mishin, et al.The Journal of Biological Chemistry|July 19, 2022
Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinalFrancis J Roushar, Andrew G McKee, Charles P Kuntz, et al.ACS Chemical Neuroscience|December 2, 2021
Discovery and Optimization of a Novel Series of Competitive and Central Nervous System-Penetrant Protease-Activated Receptor 4 (PAR4) InhibitorsJeanette L Bertron, Matthew T Duvernay, Sidnee G Mitchell, et al.The Journal of Clinical Investigation|August 15, 2024
Posttranslationally modified self-peptides promote hypertension in mouse modelsNathaniel Bloodworth, Wei Chen, Kuniko Hunter, et al.Structure (London, England : 1993)|August 14, 2020
Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific ScoringJessica A Finn, Jinhui Dong, Alexander M Sevy, et al.Journal of Medicinal Chemistry|June 20, 2023
Structure-Activity Relationship Study of the High-Affinity Neuropeptide Y4 Receptor Positive Allosteric Modulator VU0506013Corinna Schüß, Oanh Vu, Nigam M Mishra, et al.Plos Biology|January 14, 2025
Discovery of non-retinoid compounds that suppress the pathogenic effects of misfolded rhodopsin in a mouse model of retinitis pigmentosaJoseph T Ortega, Jacklyn M Gallagher, Andrew G McKee, et al.Science (New York, N.Y.)|March 8, 2014
Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulatorHuixian Wu, Chong Wang, Karen J Gregory, et al.Circulation. Cardiovascular Genetics|October 13, 2017
Predicting the Functional Impact of KCNQ1 Variants of Unknown SignificanceBian Li, Jeffrey L Mendenhall, Brett M Kroncke, et al.Pageof 44