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ACS Chemical Neuroscience|February 18, 2014
Identification of specific ligand-receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric siteKaren J Gregory, Elizabeth D Nguyen, Chrysa Malosh, et al.
ACS Chemical Neuroscience|October 1, 2011
Discovery and characterization of novel subtype-selective allosteric agonists for the investigation of M(1) receptor function in the central nervous systemEvan P Lebois, Thomas M Bridges, L Michelle Lewis, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 3, 2020
MHC-II alleles shape the CDR3 repertoires of conventional and regulatory naïve CD4+ T cellsNadezhda N Logunova, Valeriia V Kriukova, Pavel V Shelyakin, et al.
Nature Communications|March 3, 2021
Structure-function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targetingZhenfang Du, Benjamin P Brown, Soyeon Kim, et al.
The Journal of Clinical Investigation|September 4, 2013
Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza virusesNatalie J Thornburg, David P Nannemann, David L Blum, et al.
Journal of Structural Biology|May 17, 2016
The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction toolsMaximiliano Figueroa, Mike Sleutel, Marylene Vandevenne, et al.
HGG Advances|August 29, 2022
Personalized structural biology reveals the molecular mechanisms underlying heterogeneous epileptic phenotypes caused by de novo KCNC2 variantsSouhrid Mukherjee, Thomas A Cassini, Ningning Hu, et al.
Cancer Cell|June 25, 2021
Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivityAriella B Hanker, Benjamin P Brown, Jens Meiler, et al.
Plos Pathogens|May 18, 2022
Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER regionClara T Schoeder, Pavlo Gilchuk, Amandeep K Sangha, et al.
Cancer Discovery|March 10, 2017
An Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast CancerAriella B Hanker, Monica Red Brewer, Jonathan H Sheehan, et al.
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