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Jeremy L Yap

Showing results (1-10 of 21) with videos related to

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Journal of Medicinal Chemistry|October 18, 2016
Expanding the Cancer Arsenal with Targeted Therapies: Disarmament of the Antiapoptotic Bcl-2 Proteins by Small MoleculesJeremy L Yap, Lijia Chen, Maryanna E Lanning, et al.
Oncology Letters|June 1, 2018
Therapeutic potential of Bcl-x<sub>L</sub>/Mcl-1 synthetic inhibitor JY-1-106 and retinoids for human triple-negative breast cancer treatmentMariarita Perri, Jeremy L Yap, Steven Fletcher, et al.
Chemmedchem|November 27, 2010
Small-molecule inhibitors of the ERK signaling pathway: Towards novel anticancer therapeuticsJeremy L Yap, Shilpa Worlikar, Alexander D MacKerell, et al.
Experimental Cell Research|August 5, 2014
BCL-xL/MCL-1 inhibition and RARγ antagonism work cooperatively in human HL60 leukemia cellsMariarita Perri, Jeremy L Yap, Jianshi Yu, et al.
RSC Medicinal Chemistry|February 10, 2023
Discovery of <i>N</i>-sulfonylated aminosalicylic acids as dual MCL-1/BCL-xL inhibitorsLijia Chen, Jay Chauhan, Jeremy L Yap, et al.
Chemmedchem|July 1, 2014
Discovery of methyl 4'-methyl-5-(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)-[1,1'-biphenyl]-3-carboxylate, an improved small-molecule inhibitor of c-Myc-max dimerizationJay Chauhan, Huabo Wang, Jeremy L Yap, et al.
Bioorganic & Medicinal Chemistry Letters|November 27, 2012
Pharmacophore identification of c-Myc inhibitor 10074-G5Jeremy L Yap, Huabo Wang, Angela Hu, et al.
Chemmedchem|February 5, 2016
Structural Re-engineering of the α-Helix Mimetic JY-1-106 into Small Molecules: Disruption of the Mcl-1-Bak-BH3 Protein-Protein Interaction with 2,6-Di-Substituted NicotinatesBrandon Drennen, Jacob A Scheenstra, Jeremy L Yap, et al.
Organic Letters|June 15, 2013
Amphipathic α-helix mimetics based on a 1,2-diphenylacetylene scaffoldKwan-Young Jung, Kenno Vanommeslaeghe, Maryanna E Lanning, et al.
ACS Medicinal Chemistry Letters|July 21, 2015
BRD4 Structure-Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536Lijia Chen, Jeremy L Yap, Makoto Yoshioka, et al.
Pageof 3

Showing results (1-10 of 21) with videos related to

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Pageof 3
Journal of Medicinal Chemistry|October 18, 2016
Expanding the Cancer Arsenal with Targeted Therapies: Disarmament of the Antiapoptotic Bcl-2 Proteins by Small MoleculesJeremy L Yap, Lijia Chen, Maryanna E Lanning, et al.
Oncology Letters|June 1, 2018
Therapeutic potential of Bcl-x<sub>L</sub>/Mcl-1 synthetic inhibitor JY-1-106 and retinoids for human triple-negative breast cancer treatmentMariarita Perri, Jeremy L Yap, Steven Fletcher, et al.
Chemmedchem|November 27, 2010
Small-molecule inhibitors of the ERK signaling pathway: Towards novel anticancer therapeuticsJeremy L Yap, Shilpa Worlikar, Alexander D MacKerell, et al.
Experimental Cell Research|August 5, 2014
BCL-xL/MCL-1 inhibition and RARγ antagonism work cooperatively in human HL60 leukemia cellsMariarita Perri, Jeremy L Yap, Jianshi Yu, et al.
RSC Medicinal Chemistry|February 10, 2023
Discovery of <i>N</i>-sulfonylated aminosalicylic acids as dual MCL-1/BCL-xL inhibitorsLijia Chen, Jay Chauhan, Jeremy L Yap, et al.
Chemmedchem|July 1, 2014
Discovery of methyl 4'-methyl-5-(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)-[1,1'-biphenyl]-3-carboxylate, an improved small-molecule inhibitor of c-Myc-max dimerizationJay Chauhan, Huabo Wang, Jeremy L Yap, et al.
Bioorganic & Medicinal Chemistry Letters|November 27, 2012
Pharmacophore identification of c-Myc inhibitor 10074-G5Jeremy L Yap, Huabo Wang, Angela Hu, et al.
Chemmedchem|February 5, 2016
Structural Re-engineering of the α-Helix Mimetic JY-1-106 into Small Molecules: Disruption of the Mcl-1-Bak-BH3 Protein-Protein Interaction with 2,6-Di-Substituted NicotinatesBrandon Drennen, Jacob A Scheenstra, Jeremy L Yap, et al.
Organic Letters|June 15, 2013
Amphipathic α-helix mimetics based on a 1,2-diphenylacetylene scaffoldKwan-Young Jung, Kenno Vanommeslaeghe, Maryanna E Lanning, et al.
ACS Medicinal Chemistry Letters|July 21, 2015
BRD4 Structure-Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536Lijia Chen, Jeremy L Yap, Makoto Yoshioka, et al.
Pageof 3