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Jeremy L Yap

Showing results (11-20 of 21) with videos related to

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Organic & Biomolecular Chemistry|March 8, 2012
Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitorsJeremy L Yap, Xiaobo Cao, Kenno Vanommeslaeghe, et al.
BMC Cancer|November 23, 2012
The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibitionChander Peddaboina, Daniel Jupiter, Steven Fletcher, et al.
Oncotarget|June 27, 2013
Disruption of Myc-Max heterodimerization with improved cell-penetrating analogs of the small molecule 10074-G5Huabo Wang, Jay Chauhan, Angela Hu, et al.
Oncotarget|November 13, 2018
Erratum: Disruption of Myc-Max Heterodimerization with Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5Huabo Wang, Jay Chauhan, Angela Hu, et al.
Journal of Medicinal Chemistry|March 4, 2015
Perturbation of the c-Myc-Max protein-protein interaction via synthetic α-helix mimeticsKwan-Young Jung, Huabo Wang, Peter Teriete, et al.
SLAS Discovery : Advancing Life Sciences R & D|June 25, 2024
Profiling cells with DELs: Small molecule fingerprinting of cell surfacesJason Deng, Svetlana Belyanskaya, Ninad Prabhu, et al.
Molecular Cancer|May 18, 2013
The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with BakXiaobo Cao, Jeremy L Yap, M Karen Newell-Rogers, et al.
Organic & Biomolecular Chemistry|April 30, 2013
Structural modifications of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione that improve selectivity for inhibiting the proliferation of melanoma cells containing active ERK signalingKwan-Young Jung, Ramin Samadani, Jay Chauhan, et al.
European Journal of Medicinal Chemistry|March 18, 2016
Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoproteinMaryanna E Lanning, Wenbo Yu, Jeremy L Yap, et al.
ACS Medicinal Chemistry Letters|June 17, 2026
Structure-Guided Discovery of Selective Polo-Like Kinase 3 InhibitorsJeremy L Yap, Gabrielle Lovett, Jeremy W Mason, et al.
Pageof 3

Showing results (11-20 of 21) with videos related to

Sort By:
Pageof 3
Organic & Biomolecular Chemistry|March 8, 2012
Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitorsJeremy L Yap, Xiaobo Cao, Kenno Vanommeslaeghe, et al.
BMC Cancer|November 23, 2012
The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibitionChander Peddaboina, Daniel Jupiter, Steven Fletcher, et al.
Oncotarget|June 27, 2013
Disruption of Myc-Max heterodimerization with improved cell-penetrating analogs of the small molecule 10074-G5Huabo Wang, Jay Chauhan, Angela Hu, et al.
Oncotarget|November 13, 2018
Erratum: Disruption of Myc-Max Heterodimerization with Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5Huabo Wang, Jay Chauhan, Angela Hu, et al.
Journal of Medicinal Chemistry|March 4, 2015
Perturbation of the c-Myc-Max protein-protein interaction via synthetic α-helix mimeticsKwan-Young Jung, Huabo Wang, Peter Teriete, et al.
SLAS Discovery : Advancing Life Sciences R & D|June 25, 2024
Profiling cells with DELs: Small molecule fingerprinting of cell surfacesJason Deng, Svetlana Belyanskaya, Ninad Prabhu, et al.
Molecular Cancer|May 18, 2013
The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with BakXiaobo Cao, Jeremy L Yap, M Karen Newell-Rogers, et al.
Organic & Biomolecular Chemistry|April 30, 2013
Structural modifications of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione that improve selectivity for inhibiting the proliferation of melanoma cells containing active ERK signalingKwan-Young Jung, Ramin Samadani, Jay Chauhan, et al.
European Journal of Medicinal Chemistry|March 18, 2016
Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoproteinMaryanna E Lanning, Wenbo Yu, Jeremy L Yap, et al.
ACS Medicinal Chemistry Letters|June 17, 2026
Structure-Guided Discovery of Selective Polo-Like Kinase 3 InhibitorsJeremy L Yap, Gabrielle Lovett, Jeremy W Mason, et al.
Pageof 3