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Proceedings of the National Academy of Sciences of the United States of America
|
June 27, 2013
Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling
Aaron H Phillips, Yingnan Zhang, Christian N Cunningham, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 23, 2013
Identification of GNE-293, a potent and selective PI3Kδ inhibitor: navigating in vitro genotoxicity while improving potency and selectivity
Brian S Safina, Zachary K Sweeney, Jun Li, et al.
Journal of Medicinal Chemistry
|
August 11, 2012
Potent and highly selective benzimidazole inhibitors of PI3-kinase delta
Jeremy M Murray, Zachary K Sweeney, Bryan K Chan, et al.
Journal of Medicinal Chemistry
|
December 2, 2025
Discovery of Potent, Selective and Efficacious Aminopyrazole Inhibitors of PLK4
Joon Won Jeong, Trevor Chang, Jeremy M Murray, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 4, 2011
Structure-based design of thienobenzoxepin inhibitors of PI3-kinase
Steven T Staben, Michael Siu, Richard Goldsmith, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 31, 2012
Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2
Sharada Labadie, Peter S Dragovich, Kathy Barrett, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 9, 2010
Structure-based optimization of pyrazolo-pyrimidine and -pyridine inhibitors of PI3-kinase
Steven T Staben, Timothy P Heffron, Daniel P Sutherlin, et al.
Journal of Medicinal Chemistry
|
June 22, 2026
Utilizing Molecular Dynamics and Mechanistic Pharmacokinetic Studies in the Design of Selective CDK2 Inhibitors
Vishal A Verma, Jessica M Grandner, Brendan T Parr, et al.
Journal of Medicinal Chemistry
|
February 17, 2021
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy
Peter S Dragovich, Thomas H Pillow, Robert A Blake, et al.
ACS Medicinal Chemistry Letters
|
June 17, 2026
Optimization Leading to a Potent and Selective Cbl‑b Inactive-State Inhibitor That Demonstrated <i>In Vivo</i> Efficacy
Jun Liang, Michael J Lambrecht, Malcolm P Huestis, et al.
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Search research articles
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Showing results (11-20 of 21) with videos related to
Sort By:
Page
of 3
Proceedings of the National Academy of Sciences of the United States of America
|
June 27, 2013
Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling
Aaron H Phillips, Yingnan Zhang, Christian N Cunningham, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 23, 2013
Identification of GNE-293, a potent and selective PI3Kδ inhibitor: navigating in vitro genotoxicity while improving potency and selectivity
Brian S Safina, Zachary K Sweeney, Jun Li, et al.
Journal of Medicinal Chemistry
|
August 11, 2012
Potent and highly selective benzimidazole inhibitors of PI3-kinase delta
Jeremy M Murray, Zachary K Sweeney, Bryan K Chan, et al.
Journal of Medicinal Chemistry
|
December 2, 2025
Discovery of Potent, Selective and Efficacious Aminopyrazole Inhibitors of PLK4
Joon Won Jeong, Trevor Chang, Jeremy M Murray, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 4, 2011
Structure-based design of thienobenzoxepin inhibitors of PI3-kinase
Steven T Staben, Michael Siu, Richard Goldsmith, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 31, 2012
Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2
Sharada Labadie, Peter S Dragovich, Kathy Barrett, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 9, 2010
Structure-based optimization of pyrazolo-pyrimidine and -pyridine inhibitors of PI3-kinase
Steven T Staben, Timothy P Heffron, Daniel P Sutherlin, et al.
Journal of Medicinal Chemistry
|
June 22, 2026
Utilizing Molecular Dynamics and Mechanistic Pharmacokinetic Studies in the Design of Selective CDK2 Inhibitors
Vishal A Verma, Jessica M Grandner, Brendan T Parr, et al.
Journal of Medicinal Chemistry
|
February 17, 2021
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy
Peter S Dragovich, Thomas H Pillow, Robert A Blake, et al.
ACS Medicinal Chemistry Letters
|
June 17, 2026
Optimization Leading to a Potent and Selective Cbl‑b Inactive-State Inhibitor That Demonstrated <i>In Vivo</i> Efficacy
Jun Liang, Michael J Lambrecht, Malcolm P Huestis, et al.
Page
of 3